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Table 2 Estrogen receptor status, aromatase mRNA levels, and exon 1 group of cancer from the elderly according to histologic types

From: Alternative use of multiple exons 1 of aromatase gene in cancerous and normal breast tissues from women over the age of 80 years

Histologic type (n) Estrogen receptor Aromatase mRNA ± SEM, amol/mgRNA Exon 1 group
  + (%) -   d > c d c < d c b
Muc (5) 5 (100%) 0 39.1 ± 8.99 5 0 0 0 0
Others (33) 22 (67%) 11 16.8 ± 2.86 15 16 0 2 0
   Apo (7) 0 (0%) 7 20.1 ± 4.06 3 3 0 1 0
   ILC (2) 1 (50%) 1 2.45 ± 0.05 1 1 0 0 0
   IDC (24) 21 (88%) 3 17.0 ± 3.68 11 12 0 1 0
Total (38) 27 (71%) 11 19.7 ± 2.97 20 16 0 2 0
P value Muc vs. others    0.0090 S 0.0750 NS     
  1. +, positive; -, negative; Apo, apocrine carcinoma; IDC, invasive ductal carcinoma; ILC, invasive lobular carcinoma; Muc, mucinous carcinoma; NS, not significant; S, significant; SEM, standard error of the mean.