Alternative use of multiple exons 1 of aromatase gene in cancerous and normal breast tissues from women over the age of 80 years

Table 2 Estrogen receptor status, aromatase mRNA levels, and exon 1 group of cancer from the elderly according to histologic types

Histologic type (n)	Estrogen receptor		Aromatase mRNA ± SEM, amol/mgRNA	Exon 1 group
	+ (%)	-		d > c	d	c < d	c	b
Muc (5)	5 (100%)	0	39.1 ± 8.99	5	0	0	0	0
Others (33)	22 (67%)	11	16.8 ± 2.86	15	16	0	2	0
Apo (7)	0 (0%)	7	20.1 ± 4.06	3	3	0	1	0
ILC (2)	1 (50%)	1	2.45 ± 0.05	1	1	0	0	0
IDC (24)	21 (88%)	3	17.0 ± 3.68	11	12	0	1	0
Total (38)	27 (71%)	11	19.7 ± 2.97	20	16	0	2	0
P value Muc vs. others			0.0090 S	0.0750 NS

+, positive; -, negative; Apo, apocrine carcinoma; IDC, invasive ductal carcinoma; ILC, invasive lobular carcinoma; Muc, mucinous carcinoma; NS, not significant; S, significant; SEM, standard error of the mean.

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