Figure 6
From: Genomic profiling of breast tumours in relation to BRCAabnormalities and phenotypes
Hierarchical cluster analysis of genomic profiles within the simple-profiles subgroup. This analysis revealed a cluster of tumours (n = 11), purple bar and rectangle, characterised by very low genomic instability indices. This cluster was highly enriched with tumours of basal-like phenotypes with high expression of epidermal growth factor receptor (EGFR) being a prominent feature. These tumours generally displayed high tumour grade and an aggressive phenotype in terms of time to relapse.