Skip to main content

Table 1 Patient characteristics before study start

From: Stem cell and epithelial-mesenchymal transition markers are frequently overexpressed in circulating tumor cells of metastatic breast cancer patients

Patient characteristics at first diagnosis   Number
Number of patients   39
Median age (years)   46 (range, 35–78)
Staging of the primary tumor is 1
  I 5
  II 21
  III 6
  IV 6
Histology Ductal 24
  Lobular 5
  Ductal/lobular 2
  Other* 5
  Not known 3
Grading 1 4
  2 16
  3 18
  Not known 1
Receptor expression   
Estrogen and progesterone receptor Pos 26
Estrogen receptor Pos 31
Progesterone receptor Pos 26
HER2 overexpression Pos (3+) 11
  DAKO 2+/FISH- 3
Sites of metastasis   
Visceral + nonvisceral   21
Visceral   11
Nonvisceral   7
Cerebral   0
Elevated markers CEA 25
  Ca15-3 27
  Not known 1
Treatment   
(Neo-)adjuvant treatment at primary diagnosis   
Chemotherapy   19
Radiation   11
Hormone   18
Trastuzumab   1
Not known   0
Treatment in the metastatic setting   
Chemotherapy line First 13
  Second 4
  Third 6
  Fourth and more 12
  Not known 0
Trastuzumab   11
Hormone therapy   23
  1. *Medular, trabecular, secretory, neuroendocrine, adenocarcinoma.