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Table 4 Univariate Cox proportional hazard analysis (disease-free survival) in the whole breast cancer series

From: Expression of FOXA1 and GATA-3 in breast cancer: the prognostic significance in hormone receptor-negative tumours

Variable Evaluation Hazard ratio (95% confidence interval) P value
Tumour size T1 (≤ 2 mm) 1  
  T2 (2 < T ≤ 5 mm) 1.57 (0.70 to 3.51) 0.265
  T3 (>5 mm) 3.12 (1.16 to 8.41) 0.024
Lymph node stage Negative 1  
  1 to 3 lymph nodes 0.56 (0.20 to 1.56) 0.272
  >3 lymph nodes 2.68 (1.30 to 5.49) 0.007
Tumour grade Grade I 1  
  Grade II 2.60 (0.58 to 11.56) 0.208
  Grade III 7.65 (1.80 to 32.48) 0.006
ER expression ER-positive 1  
  ER-negative 2.94 (1.52 to 5.57) 0.001
PR expression PR-positive 1  
  PR-negative 2.16 (1.04 to 4.46) 0.038
HER-2/neu expression HER-2/neu-negative 1  
  HER-2/neu-positive 2.47 (1.19 to 5.09) 0.014
FOXA1 expression FOXA1-positive 1  
  FOXA1-negative 4.25 (1.76 to 10.28) 0.001
GATA-3 expression GATA-3-positive 1  
  GATA-3-negative 1.97 (0.96 to 4.01) 0.061
  1. ER, oestrogen receptor; FOXA-1, forkhead box A1; GATA-3, GATA binding protein 3; HER-2, human epidermal growth factor receptor 2; PR, progesterone receptor.