Table 4 Univariate Cox proportional hazard analysis (disease-free survival) in the whole breast cancer series
Variable | Evaluation | Hazard ratio (95% confidence interval) | P value |
|---|---|---|---|
Tumour size | T1 (≤ 2 mm) | 1 | |
T2 (2 < T ≤ 5 mm) | 1.57 (0.70 to 3.51) | 0.265 | |
T3 (>5 mm) | 3.12 (1.16 to 8.41) | 0.024 | |
Lymph node stage | Negative | 1 | |
1 to 3 lymph nodes | 0.56 (0.20 to 1.56) | 0.272 | |
>3 lymph nodes | 2.68 (1.30 to 5.49) | 0.007 | |
Tumour grade | Grade I | 1 | |
Grade II | 2.60 (0.58 to 11.56) | 0.208 | |
Grade III | 7.65 (1.80 to 32.48) | 0.006 | |
ER expression | ER-positive | 1 | |
ER-negative | 2.94 (1.52 to 5.57) | 0.001 | |
PR expression | PR-positive | 1 | |
PR-negative | 2.16 (1.04 to 4.46) | 0.038 | |
HER-2/neu expression | HER-2/neu-negative | 1 | |
HER-2/neu-positive | 2.47 (1.19 to 5.09) | 0.014 | |
FOXA1 expression | FOXA1-positive | 1 | |
FOXA1-negative | 4.25 (1.76 to 10.28) | 0.001 | |
GATA-3 expression | GATA-3-positive | 1 | |
GATA-3-negative | 1.97 (0.96 to 4.01) | 0.061 |