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Table 2 Trends in the incidence and proportion of HER-2-positive breast cancer from 1982 to 2005 in the Pirkanmaa Hospital District

From: HER-2 positive breast cancer: decreasing proportion but stable incidence in Finnish population from 1982 to 2005

Breast cancer cohort Mean annual age-adjusted incidence*
(per 100,000)
Proportion of HER-2-positive breast cancers Estimated age-adjusted incidence of HER-2-positive breast cancer
(per 100,000)**
Estimated age-adjusted incidence of HER-2-negative breast cancer
(per 100,000)**
1982 to 1986 56.3 21.6% (67/310) 12.2 44.1
1989 to 1992 68.9 17.6% (19/108) 12.1 56.8
2004 to 2005 95.3 13.6% (97/713) 13.0 82.3
  1. * Data from the Finnish Cancer Registry, age-adjusted to the world standard population; ** Estimated by multiplying the incidence of all breast cancers and the proportion of HER-2 positive.
  2. HER-2 = human epidermal growth factor receptor 2.