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Table 2 Trends in the incidence and proportion of HER-2-positive breast cancer from 1982 to 2005 in the Pirkanmaa Hospital District

From: HER-2 positive breast cancer: decreasing proportion but stable incidence in Finnish population from 1982 to 2005

Breast cancer cohort

Mean annual age-adjusted incidence*

(per 100,000)

Proportion of HER-2-positive breast cancers

Estimated age-adjusted incidence of HER-2-positive breast cancer

(per 100,000)**

Estimated age-adjusted incidence of HER-2-negative breast cancer

(per 100,000)**

1982 to 1986

56.3

21.6% (67/310)

12.2

44.1

1989 to 1992

68.9

17.6% (19/108)

12.1

56.8

2004 to 2005

95.3

13.6% (97/713)

13.0

82.3

  1. * Data from the Finnish Cancer Registry, age-adjusted to the world standard population; ** Estimated by multiplying the incidence of all breast cancers and the proportion of HER-2 positive.
  2. HER-2 = human epidermal growth factor receptor 2.