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Table 1 Characteristics of the study cohorts

From: HER-2 positive breast cancer: decreasing proportion but stable incidence in Finnish population from 1982 to 2005

Patient cohort (year of primary diagnosis)

Female

population*

Number of breast

cancers diagnosed per year**

Number of breast cancers in the cohort

(n, %)**

Age at diagnosis (median, range)

Proportion of axillary lymph node negative cancers

Proportion of estrogen receptor-positive cancers

Proportion of progesterone receptor-positive cancers

1982 to 1986

       

population-based**

215,639

191

957

63 (27 to 92)

53.1%

NA

NA

studied cohort

  

310 (32.4%)

59 (30 to 88)

56.6%

59.4%

69.7%

1989 to 1992

       

population-based**,***

220,257

246

985

60 (28 to 92)

58.9%

72.0%

63.0%

studied cohort

  

108 (11.0%)

64 (34 to 88)

65.2%

77.9%

55.9%

2004 to 2005

       

population-based**

231,000

389

777

NA

NA

NA

NA

studied cohort

  

713 (91.8%)

60 (25 to 94)

56.3%

89.8%****

77.3%

  1. * Data from Statistics Finland (Pirkanmaa hospital district, Finland); ** Data from the Finnish Cancer Registry; *** Data from Laboratory of Cancer Biology, University of Tampere; **** The trend is statistically significant (P < 0.0001).
  2. NA = not available.