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Table 1 Characteristics of the study cohorts

From: HER-2 positive breast cancer: decreasing proportion but stable incidence in Finnish population from 1982 to 2005

Patient cohort (year of primary diagnosis) Female
population*
Number of breast
cancers diagnosed per year**
Number of breast cancers in the cohort
(n, %)**
Age at diagnosis (median, range) Proportion of axillary lymph node negative cancers Proportion of estrogen receptor-positive cancers Proportion of progesterone receptor-positive cancers
1982 to 1986        
population-based** 215,639 191 957 63 (27 to 92) 53.1% NA NA
studied cohort    310 (32.4%) 59 (30 to 88) 56.6% 59.4% 69.7%
1989 to 1992        
population-based**,*** 220,257 246 985 60 (28 to 92) 58.9% 72.0% 63.0%
studied cohort    108 (11.0%) 64 (34 to 88) 65.2% 77.9% 55.9%
2004 to 2005        
population-based** 231,000 389 777 NA NA NA NA
studied cohort    713 (91.8%) 60 (25 to 94) 56.3% 89.8%**** 77.3%
  1. * Data from Statistics Finland (Pirkanmaa hospital district, Finland); ** Data from the Finnish Cancer Registry; *** Data from Laboratory of Cancer Biology, University of Tampere; **** The trend is statistically significant (P < 0.0001).
  2. NA = not available.