Extended adjuvant hormonal therapy with exemestane has no detrimental effect on the lipid profile of postmenopausal breast cancer patients: final results of the ATENA lipid substudy

Table 4 Estimated differences between treatments of mean absolute values for lipid parameters across the study period according to the mixed-effects model (mean ± standard error).

		Cholesterol value	HDL value	LDL value	Total TRG value
		E-O^a	E-O	E-O^a	E-O^a
Baseline	Mean ± SEM		-0.25 ± 1.36
	P		0.85
6 months	Mean ± SEM		-2.96 ± 1.07
	P		0.01
12 months	Mean ± SEM	-1.23 ± 2.93	-5.68 ± 1.35	7.77 ± 4.42	-0.02 ± 0.03
	P	0.68	<0.0001	0.08	0.50
18 months	Mean ± SEM		-8.39 ± 1.97
	P		<0.0001
24 months	Mean ± SEM		-11.1 ± 2.7
	P		<0.0001

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