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Table 4 Estimated differences between treatments of mean absolute values for lipid parameters across the study period according to the mixed-effects model (mean ± standard error).

From: Extended adjuvant hormonal therapy with exemestane has no detrimental effect on the lipid profile of postmenopausal breast cancer patients: final results of the ATENA lipid substudy

   Cholesterol value HDL value LDL value Total TRG value
   E-Oa E-O E-Oa E-Oa
Baseline Mean ± SEM   -0.25 ± 1.36   
  P   0.85   
6 months Mean ± SEM   -2.96 ± 1.07   
  P   0.01   
12 months Mean ± SEM -1.23 ± 2.93 -5.68 ± 1.35 7.77 ± 4.42 -0.02 ± 0.03
  P 0.68 <0.0001 0.08 0.50
18 months Mean ± SEM   -8.39 ± 1.97   
  P   <0.0001   
24 months Mean ± SEM   -11.1 ± 2.7   
  P   <0.0001   
  1. E = exemestane; O = observation.
  2. aNote: Constant difference between E and O across time.