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Table 1 Clinicopathological parameters of cryo-conserved breast cancer specimens (n = 128)

From: Frequent loss of endothelin-3 (EDN3) expression due to epigenetic inactivation in human breast cancer

Variables Numbera Percentage
Clinicopathological factors   
   Age at diagnosisb   
< 58 years 64 50.0
≥ 58 years 64 50.0
   Tumour sizec   
pT1 44 34.4
pT2 55 43.0
pT3 6 4.7
pT4 11 8.6
pTx 12 9.4
   Lymph node statusc   
pN0 57 44.5
pN1–3 51 39.8
pNx 20 15.6
   Histological grade   
G1 10 7.8
G2 58 45.3
G3 49 38.3
NA 11 8.6
   Histological type   
Ductal 103 80.5
Lobular 15 11.7
Other 6 4.7
NA 4 3.1
Immunohistochemistry   
   Oestrogen receptor   
Negative (IRSd ≤ 2) 33 25.8
Positive (IRS > 2) 85 66.4
NA 10 7.8
Progesterone receptor   
Negative (IRSd ≤ 2) 33 25.8
Positive (IRS > 2) 85 66.4
NA 10 7.8
  1. Due to rounding, percentages may not sum to 100. aOnly female patients with primary invasive breast cancer were included. bMedian 58 years, range 28 to 87 years. cAccording to the UICC (Union Internationale contre le Cancer): TNM Classification of Malignant Tumours [19].dImmunoreactivity score (IRS) according to Remmele and Stegner [24]. NA, information not available.