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Table 2 Mammary differentiation specific gene expression

From: Gene expression in murine mammary epithelial stem cell-like cells shows similarities to human breast cancer gene expression

Symbol

Gene

2logFC

Gene ontology

Expi

Extracellular proteinase inhibitor

5.01

Protease inhibitor activity

Gas6

Growth arrest specific 6

3.14

Regulation of cell growth

Slc6a6

Solute carrier family 6, member 6

2.88

Neurotransmitter transport

Ehf

Ets homologous factor

3.66

Transcription factor activity

Ctsd

Cathepsin D

2.88

Proteolysis

Xdh

Xanthine dehydrogenase

1.83

Lactation/regulation of epithelial cell differentiation

D0H4S114

Dna segment, human D4S114

3.32

Regulation of Tgf-b signaling pathway

Nupr1

Nuclear protein 1

1.92

Not defined

H2-T23

Histocompatibility 2, T region locus 23

1.75

Antigen processing and presentation

Atp6v0d1

ATPase, H transporting, V0 subunit D isoform 1

1.78

Proton transport

Cd81

CD 81 antigen

2.03

Positive regulation of cell growth

D12Ertd647e

DNA segment, Chr 12, ERATO Doi 647, expressed, transcript variant 3

2.22

Not defined

Cbr2

Carbonyl reductase 2

2.92

Metabolic process

Plagl1

Pleiomorphic adenoma gene-like 1

2.43

Positive regulation of transcription from RNA polymerase II promoter

Atp6v1a1

ATPase, H transporting, V1 subunit A, isoform 1

1.96

Proton transport

Ctsa

Cathepsin A

2.17

Proteolysis

Stat1

Signal transducer and activator of transcription 1

1.56

Transcription

Oas1a

2',5' -Oligoadenylate synthetase 1A

1.61

Negative regulation of viral reproduction

Ddx58

DEAD box polypeptide 58

1.90

Immune response

Tmem154

Transmembrane protein 154

1.76

Not defined

Fcgrt

Fc receptor, IgG, alpha chain transporter

1.41

Immune response

Itm2b

Integral membrane protein 2B

2.45

Induction of apoptosis

Sema6a

Sema domain, transmembrane domain and cytoplasmic domain (semaphorin) 6A

1.52

Cell differentiation/apoptosis

Cuedc1

CUE domain containing 1

1.54

Not defined

Rtp4

Receptor transporter protein 4

1.96

Not defined

  1. Genes that increase strongly upon initiation of differentiation. 2logFC denotes the 2log of fold-change (a value of 2 equals a fourfold upregulation or a 400% increase during differentiation).