Variable | NE (%) | Classes | N (%) | Hazard Ratio [IC95] | p-value × |
---|---|---|---|---|---|
Age | 0 (0%) | < 45 years | 29 (8%) | 1 | 0.964 |
>= 45 years | 355 (92%) | 1.02 [0.401–2.605] | |||
< 45 | 29 (8%) | 1 | 0.315 | ||
45–60 | 155 (40%) | 0.834 [0.312–2.226] | |||
> 60 | 200 (52%) | 1.32 [0.493–3.522] | |||
Tumoral size | 2 (1%) | < 25 mm | 141 (37%) | 1 | 0.0222 |
>= 25 mm | 241 (63%) | 2.16 [1.1–4.23] | |||
Scarff-Bloom-Richardson grade | 2 (1%) | I | 141 (37%) | 1 | 0.000487 |
II–III | 241 (63%) | 4.1 [1.74–9.644] | |||
VPI | 3 (1%) | absent | 237 (62%) | 1 | 0.00363 |
present | 144 (38%) | 2.36 [1.305–4.268] | |||
N | 3 (1%) | N- | 174 (46%) | 1 | 0.0495 |
N+ | 207 (54%) | 2.22 [1–4.921] | |||
N < 3 | 288 (76%) | 1 | < 0.0001 | ||
N >= 3 | 93 (24%) | 3.81 [2.113–6.883] | |||
AR | 66 (17%) | 0 | 74 (23%) | 1 | 0.306 |
> 0 | 244 (77%) | 0.712 [0.371–1.369] | |||
BCL2 | 66 (17%) | 0 | 38 (12%) | 1 | 0.0676 |
> 0 | 280 (88%) | 0.492 [0.226–1.069] | |||
CCND1 | 47 (12%) | 0 | 97 (29%) | 1 | 0.971 |
> 0 | 240 (71%) | 1.01 [0.542–1.886] | |||
ERBB2 | 36 (9%) | 1 or 2 | 319 (92%) | 1 | 0.558 |
2 or 3 | 29 (8%) | 1.32 [0.519–3.359] | |||
FOXA1 | 78 (20%) | 0 | 3 (1%) | 1 | 0.406 |
> 0 | 303 (99%) | 9220000 [0-Inf] | |||
GATA3 | 66 (17%) | 0 | 70 (22%) | 1 | 0.0952 |
> 0 | 248 (78%) | 0.599 [0.326–1.1] | |||
Ki67 | 60 (16%) | < 20 | 299 (92%) | 1 | 0.000304 |
>= 20 | 25 (8%) | 3.58 [1.709–7.488] | |||
P53 | 55 (14%) | 0 | 272 (83%) | 1 | < 0001 |
> 0 | 57 (17%) | 3.13 [1.745–5.601] | |||
ER | 0 (0%) | < 120 | 153 (40%) | 1 | 0.227 |
>= 120 | 231 (60%) | 0.71 [0.406–1.24] | |||
PR | 44 (11%) | 0 | 76 (22%) | 1 | 0.941 |
> 0 | 264 (78%) | 0.975 [0.499–1.904] |