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Table 1 List of biomarkers in 35-plex panel

From: The multiplex bead array approach to identifying serum biomarkers associated with breast cancer

Marker list
Oncofetal protein Acute phase protein
Alpha-fetoprotein (AFP) Alpha-1-antitrypin (A1AT)a
Carcinoembryonic antigen (CEA) Alpha-2 macroglobulin (A2M)c
Cancer antigen 125 (CA125)c C-reactive protein (CRP)b
Cancer antigen 19-9 (CA19-9)c D-dimer (DD)c
Prostate-specific antigen (PSA)c Haptoglobin α (Hp)a
Cytokine Serum amyloid A (SAA)b
Interleukin-1β (IL-1β)c Transthyretin (TTR)a
Interleukin-1 receptor α (IL-Rα)c Coagulation/thrombosis
Interleukin-6 (IL-6)c Haemoglobin (Hg)b
Interleukin-8 (IL-8)c High-molecular-weight kininogen (HMWK)c
Monocyte chemotactic protein-1
(MCP-1)c
Plasminogen activator inhibitor-1
(PAI-1)c
Monocyte inflammatory protein-1α (MIP-1α)c Metabolism
Immune/inflammation Apolipoprotein A1 (ApoA1)c
Soluble CD40 ligand (sCD40L)c Pro-apolipoprotein A1 (proApoA1)a
β2-microglobulin (β 2M)b Apolipoprotein A4 (ApoA4)a
Myeloperoxidase (MPO)c Apolipoprotein H (ApoH)b
Factor/hormone Carrier
Epidermal growth factor (EGF)c Vitamin D-binding protein (VDBP)b
Adiponectinc Enzyme
Adhesion Cathepsin B (CB)c
Vitronectin (VN)c  
Soluble vascular cell adhesion molecule-1 (sVCAM-1)c  
Soluble intercellular cell adhesion molecule-1 (sICAM-1)c  
  1. aMarkers were discovered through two-dimensional polyacrylamide gel electrophoresis (2D-PAGE) using the serum of breast cancer patients. bMarkers were discovered through surface-enhanced laser desorption/ionisation time-of-flight (SELDI-TOF) mass spectrometry. cMarkers were selected using literature search.