TY - JOUR AU - Levy, L. AU - Hill, C. S. PY - 2006 DA - 2006// TI - Alterations in components of the TGF-beta superfamily signaling pathways in human cancer JO - Cytokine Growth Factor Rev VL - 17 UR - https://doi.org/10.1016/j.cytogfr.2005.09.009 DO - 10.1016/j.cytogfr.2005.09.009 ID - Levy2006 ER - TY - JOUR AU - Serra, R. AU - Crowley, M. R. PY - 2005 DA - 2005// TI - Mouse models of transforming growth factor beta impact in breast development and cancer JO - Endocr Relat Cancer VL - 12 UR - https://doi.org/10.1677/erc.1.00936 DO - 10.1677/erc.1.00936 ID - Serra2005 ER - TY - JOUR AU - Gobbi, H. AU - Dupont, W. D. AU - Simpson, J. F. AU - Plummer, W. D. AU - Schuyler, P. A. AU - Olson, S. J. AU - Arteaga, C. L. AU - Page, D. L. PY - 1999 DA - 1999// TI - Transforming growth factor-beta and breast cancer risk in women with mammary epithelial hyperplasia JO - J Natl Cancer Inst VL - 91 UR - https://doi.org/10.1093/jnci/91.24.2096 DO - 10.1093/jnci/91.24.2096 ID - Gobbi1999 ER - TY - JOUR AU - Gobbi, H. AU - Arteaga, C. L. AU - Jensen, R. A. AU - Simpson, J. F. AU - Dupont, W. D. AU - Olson, S. J. AU - Schuyler, P. A. AU - Plummer, W. D. AU - Page, D. L. PY - 2000 DA - 2000// TI - Loss of expression of transforming growth factor beta type II receptor correlates with high tumour grade in human breast in-situ and invasive carcinomas JO - Histopathology VL - 36 UR - https://doi.org/10.1046/j.1365-2559.2000.00841.x DO - 10.1046/j.1365-2559.2000.00841.x ID - Gobbi2000 ER - TY - JOUR AU - Roarty, K. AU - Serra, R. PY - 2007 DA - 2007// TI - Wnt5a is required for proper mammary gland development and TGF-beta-mediated inhibition of ductal growth JO - Development VL - 134 UR - https://doi.org/10.1242/dev.008250 DO - 10.1242/dev.008250 ID - Roarty2007 ER - TY - JOUR AU - Gordon, M. D. AU - Nusse, R. PY - 2006 DA - 2006// TI - Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors JO - J Biol Chem VL - 281 UR - https://doi.org/10.1074/jbc.R600015200 DO - 10.1074/jbc.R600015200 ID - Gordon2006 ER - TY - JOUR AU - Ishitani, T. AU - Kishida, S. AU - Hyodo-Miura, J. AU - Ueno, N. AU - Yasuda, J. AU - Waterman, M. AU - Shibuya, H. AU - Moon, R. T. AU - Ninomiya-Tsuji, J. AU - Matsumoto, K. PY - 2003 DA - 2003// TI - The TAK1-NLK mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca(2+) pathway to antagonize Wnt/beta-catenin signaling JO - Mol Cell Biol VL - 23 UR - https://doi.org/10.1128/MCB.23.1.131-139.2003 DO - 10.1128/MCB.23.1.131-139.2003 ID - Ishitani2003 ER - TY - JOUR AU - Mikels, A. J. AU - Nusse, R. PY - 2006 DA - 2006// TI - Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context JO - PLoS Biol VL - 4 UR - https://doi.org/10.1371/journal.pbio.0040115 DO - 10.1371/journal.pbio.0040115 ID - Mikels2006 ER - TY - JOUR AU - Nemeth, M. J. AU - Topol, L. AU - Anderson, S. M. AU - Yang, Y. AU - Bodine, D. M. PY - 2007 DA - 2007// TI - Wnt5a inhibits canonical Wnt signaling in hematopoietic stem cells and enhances repopulation JO - Proc Natl Acad Sci USA VL - 104 UR - https://doi.org/10.1073/pnas.0704747104 DO - 10.1073/pnas.0704747104 ID - Nemeth2007 ER - TY - JOUR AU - Topol, L. AU - Jiang, X. AU - Choi, H. AU - Garrett-Beal, L. AU - Carolan, P. J. AU - Yang, Y. PY - 2003 DA - 2003// TI - Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation JO - J Cell Biol VL - 162 UR - https://doi.org/10.1083/jcb.200303158 DO - 10.1083/jcb.200303158 ID - Topol2003 ER - TY - JOUR AU - Olson, D. J. AU - Gibo, D. M. PY - 1998 DA - 1998// TI - Antisense wnt-5a mimics wnt-1-mediated C57MG mammary epithelial cell transformation JO - Exp Cell Res VL - 241 UR - https://doi.org/10.1006/excr.1998.4030 DO - 10.1006/excr.1998.4030 ID - Olson1998 ER - TY - JOUR AU - Jonsson, M. AU - Dejmek, J. AU - Bendahl, P. O. AU - Andersson, T. PY - 2002 DA - 2002// TI - Loss of Wnt-5a protein is associated with early relapse in invasive ductal breast carcinomas JO - Cancer Res VL - 62 ID - Jonsson2002 ER - TY - JOUR AU - Leris, A. C. AU - Roberts, T. R. AU - Jiang, W. G. AU - Newbold, R. F. AU - Mokbel, K. PY - 2005 DA - 2005// TI - WNT5A expression in human breast cancer JO - Anticancer Res VL - 25 ID - Leris2005 ER - TY - JOUR AU - Pukrop, T. AU - Klemm, F. AU - Hagemann, T. AU - Gradl, D. AU - Schulz, M. AU - Siemes, S. AU - Trumper, L. AU - Binder, C. PY - 2006 DA - 2006// TI - Wnt 5a signaling is critical for macrophage-induced invasion of breast cancer cell lines JO - Proc Natl Acad Sci USA VL - 103 UR - https://doi.org/10.1073/pnas.0509703103 DO - 10.1073/pnas.0509703103 ID - Pukrop2006 ER - TY - JOUR AU - Weeraratna, A. T. AU - Jiang, Y. AU - Hostetter, G. AU - Rosenblatt, K. AU - Duray, P. AU - Bittner, M. AU - Trent, J. M. PY - 2002 DA - 2002// TI - Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma JO - Cancer Cell VL - 1 UR - https://doi.org/10.1016/S1535-6108(02)00045-4 DO - 10.1016/S1535-6108(02)00045-4 ID - Weeraratna2002 ER - TY - JOUR AU - Crowley, M. R. AU - Frost, A. AU - Chen, D. T. AU - Baffi, M. O. AU - Nicola, T. AU - Serra, R. PY - 2006 DA - 2006// TI - Transforming growth factor-beta signaling helps specify tumor type in DMBA and hormone-induced mammary cancers JO - Differentiation VL - 74 UR - https://doi.org/10.1111/j.1432-0436.2006.00056.x DO - 10.1111/j.1432-0436.2006.00056.x ID - Crowley2006 ER - TY - JOUR AU - Joseph, H. AU - Gorska, A. E. AU - Sohn, P. AU - Moses, H. L. AU - Serra, R. PY - 1999 DA - 1999// TI - Overexpression of a kinase-deficient transforming growth factor-beta type II receptor in mouse mammary stroma results in increased epithelial branching JO - Mol Biol Cell VL - 10 UR - https://doi.org/10.1091/mbc.10.4.1221 DO - 10.1091/mbc.10.4.1221 ID - Joseph1999 ER - TY - JOUR AU - Deome, K. B. AU - Faulkin, L. J. AU - Bern, H. A. AU - Blair, P. B. PY - 1959 DA - 1959// TI - Development of mammary tumors from hyperplastic alveolar nodules transplanted into gland-free mammary fat pads of female C3H mice JO - Cancer Res VL - 19 ID - Deome1959 ER - TY - JOUR AU - Varticovski, L. AU - Hollingshead, M. G. AU - Robles, A. I. AU - Wu, X. AU - Cherry, J. AU - Munroe, D. J. AU - Lukes, L. AU - Anver, M. R. AU - Carter, J. P. AU - Borgel, S. D. AU - Stotler, H. AU - Bonomi, C. A. AU - Nunez, N. P. AU - Hursting, S. D. AU - Qiao, W. AU - Deng, C. X. AU - Green, J. E. AU - Hunter, K. W. AU - Merlino, G. AU - Steeg, P. S. AU - Wakefield, L. M. AU - Barrett, J. C. PY - 2007 DA - 2007// TI - Accelerated preclinical testing using transplanted tumors from genetically engineered mouse breast cancer models JO - Clin Cancer Res VL - 13 UR - https://doi.org/10.1158/1078-0432.CCR-06-0918 DO - 10.1158/1078-0432.CCR-06-0918 ID - Varticovski2007 ER - TY - JOUR AU - Xie, J. AU - Haslam, S. Z. PY - 1997 DA - 1997// TI - Extracellular matrix regulates ovarian hormone-dependent proliferation of mouse mammary epithelial cells JO - Endocrinology VL - 138 ID - Xie1997 ER - TY - JOUR AU - Bijur, G. N. AU - Jope, R. S. PY - 2001 DA - 2001// TI - Proapoptotic stimuli induce nuclear accumulation of glycogen synthase kinase-3 beta JO - J Biol Chem VL - 276 UR - https://doi.org/10.1074/jbc.M105725200 DO - 10.1074/jbc.M105725200 ID - Bijur2001 ER - TY - JOUR AU - Guy, C. T. AU - Webster, M. A. AU - Schaller, M. AU - Parsons, T. J. AU - Cardiff, R. D. AU - Muller, W. J. PY - 1992 DA - 1992// TI - Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease JO - Proc Natl Acad Sci USA VL - 89 UR - https://doi.org/10.1073/pnas.89.22.10578 DO - 10.1073/pnas.89.22.10578 ID - Guy1992 ER - TY - JOUR AU - Guy, C. T. AU - Cardiff, R. D. AU - Muller, W. J. PY - 1992 DA - 1992// TI - Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease JO - Mol Cell Biol VL - 12 UR - https://doi.org/10.1128/MCB.12.3.954 DO - 10.1128/MCB.12.3.954 ID - Guy1992 ER - TY - JOUR AU - Li, Y. AU - Hively, W. P. AU - Varmus, H. E. PY - 2000 DA - 2000// TI - Use of MMTV-Wnt-1 transgenic mice for studying the genetic basis of breast cancer JO - Oncogene VL - 19 UR - https://doi.org/10.1038/sj.onc.1203273 DO - 10.1038/sj.onc.1203273 ID - Li2000 ER - TY - JOUR AU - Chu, E. Y. AU - Hens, J. AU - Andl, T. AU - Kairo, A. AU - Yamaguchi, T. P. AU - Brisken, C. AU - Glick, A. AU - Wysolmerski, J. J. AU - Millar, S. E. PY - 2004 DA - 2004// TI - Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis JO - Development VL - 131 UR - https://doi.org/10.1242/dev.01347 DO - 10.1242/dev.01347 ID - Chu2004 ER - TY - JOUR AU - He, T. C. AU - Sparks, A. B. AU - Rago, C. AU - Hermeking, H. AU - Zawel, L. AU - da Costa, L. T. AU - Morin, P. J. AU - Vogelstein, B. AU - Kinzler, K. W. PY - 1998 DA - 1998// TI - Identification of c-MYC as a target of the APC pathway JO - Science VL - 281 UR - https://doi.org/10.1126/science.281.5382.1509 DO - 10.1126/science.281.5382.1509 ID - He1998 ER - TY - JOUR AU - Saegusa, M. AU - Hashimura, M. AU - Kuwata, T. AU - Hamano, M. AU - Okayasu, I. PY - 2005 DA - 2005// TI - Upregulation of TCF4 expression as a transcriptional target of beta-catenin/p300 complexes during trans-differentiation of endometrial carcinoma cells JO - Lab Invest VL - 85 UR - https://doi.org/10.1038/labinvest.3700273 DO - 10.1038/labinvest.3700273 ID - Saegusa2005 ER - TY - JOUR AU - Welm, B. E. AU - Tepera, S. B. AU - Venezia, T. AU - Graubert, T. A. AU - Rosen, J. M. AU - Goodell, M. A. PY - 2002 DA - 2002// TI - Sca-1(pos) cells in the mouse mammary gland represent an enriched progenitor cell population JO - Dev Biol VL - 245 UR - https://doi.org/10.1006/dbio.2002.0625 DO - 10.1006/dbio.2002.0625 ID - Welm2002 ER - TY - JOUR AU - Li, Y. AU - Welm, B. AU - Podsypanina, K. AU - Huang, S. AU - Chamorro, M. AU - Zhang, X. AU - Rowlands, T. AU - Egeblad, M. AU - Cowin, P. AU - Werb, Z. AU - Tan, L. K. AU - Rosen, J. M. AU - Varmus, H. E. PY - 2003 DA - 2003// TI - Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells JO - Proc Natl Acad Sci USA VL - 100 UR - https://doi.org/10.1073/pnas.2136825100 DO - 10.1073/pnas.2136825100 ID - Li2003 ER - TY - JOUR AU - Imbert, A. AU - Eelkema, R. AU - Jordan, S. AU - Feiner, H. AU - Cowin, P. PY - 2001 DA - 2001// TI - Delta N89 beta-catenin induces precocious development, differentiation, and neoplasia in mammary gland JO - J Cell Biol VL - 153 UR - https://doi.org/10.1083/jcb.153.3.555 DO - 10.1083/jcb.153.3.555 ID - Imbert2001 ER - TY - JOUR AU - Hsu, W. AU - Shakya, R. AU - Costantini, F. PY - 2001 DA - 2001// TI - Impaired mammary gland and lymphoid development caused by inducible expression of Axin in transgenic mice JO - J Cell Biol VL - 155 UR - https://doi.org/10.1083/jcb.200107066 DO - 10.1083/jcb.200107066 ID - Hsu2001 ER - TY - JOUR AU - Ko, T. C. AU - Sheng, H. M. AU - Reisman, D. AU - Thompson, E. A. AU - Beauchamp, R. D. PY - 1995 DA - 1995// TI - Transforming growth factor-beta 1 inhibits cyclin D1 expression in intestinal epithelial cells JO - Oncogene VL - 10 ID - Ko1995 ER - TY - JOUR AU - Pietenpol, J. A. AU - Holt, J. T. AU - Stein, R. W. AU - Moses, H. L. PY - 1990 DA - 1990// TI - Transforming growth factor beta 1 suppression of c-myc gene transcription: role in inhibition of keratinocyte proliferation JO - Proc Natl Acad Sci USA VL - 87 UR - https://doi.org/10.1073/pnas.87.10.3758 DO - 10.1073/pnas.87.10.3758 ID - Pietenpol1990 ER - TY - JOUR AU - Ling, M. T. AU - Wang, X. AU - Tsao, S. W. AU - Wong, Y. C. PY - 2002 DA - 2002// TI - Down-regulation of Id-1 expression is associated with TGF beta 1-induced growth arrest in prostate epithelial cells JO - Biochim Biophys Acta VL - 1570 UR - https://doi.org/10.1016/S0304-4165(02)00189-7 DO - 10.1016/S0304-4165(02)00189-7 ID - Ling2002 ER - TY - JOUR AU - Dong, Y. AU - Drissi, H. AU - Chen, M. AU - Chen, D. AU - Zuscik, M. J. AU - Schwarz, E. M. AU - O'Keefe, R. J. PY - 2005 DA - 2005// TI - Wnt-mediated regulation of chondrocyte maturation: modulation by TGF-beta JO - J Cell Biochem VL - 95 UR - https://doi.org/10.1002/jcb.20466 DO - 10.1002/jcb.20466 ID - Dong2005 ER - TY - JOUR AU - Falk, S. AU - Wurdak, H. AU - Ittner, L. M. AU - Ille, F. AU - Sumara, G. AU - Schmid, M. T. AU - Draganova, K. AU - Lang, K. S. AU - Paratore, C. AU - Leveen, P. AU - Suter, U. AU - Karlsson, S. AU - Born, W. AU - Ricci, R. AU - Gotz, M. AU - Sommer, L. PY - 2008 DA - 2008// TI - Brain area-specific effect of TGF-beta signaling on Wnt-dependent neural stem cell expansion JO - Cell Stem Cell VL - 2 UR - https://doi.org/10.1016/j.stem.2008.03.006 DO - 10.1016/j.stem.2008.03.006 ID - Falk2008 ER - TY - JOUR AU - Wang, H. AU - Rajan, S. AU - Liu, G. AU - Chakrabarty, S. PY - 2008 DA - 2008// TI - Transforming growth factor beta suppresses beta-catenin/Wnt signaling and stimulates an adhesion response in human colon carcinoma cells in a Smad4/DPC4 independent manner JO - Cancer Lett VL - 264 UR - https://doi.org/10.1016/j.canlet.2008.01.039 DO - 10.1016/j.canlet.2008.01.039 ID - Wang2008 ER - TY - JOUR AU - Liu, Z. AU - Tang, Y. AU - Qiu, T. AU - Cao, X. AU - Clemens, T. L. PY - 2006 DA - 2006// TI - A dishevelled-1/Smad1 interaction couples WNT and bone morphogenetic protein signaling pathways in uncommitted bone marrow stromal cells JO - J Biol Chem VL - 281 UR - https://doi.org/10.1074/jbc.M513812200 DO - 10.1074/jbc.M513812200 ID - Liu2006 ER - TY - JOUR AU - Labbe, E. AU - Lock, L. AU - Letamendia, A. AU - Gorska, A. E. AU - Gryfe, R. AU - Gallinger, S. AU - Moses, H. L. AU - Attisano, L. PY - 2007 DA - 2007// TI - Transcriptional cooperation between the transforming growth factor-beta and Wnt pathways in mammary and intestinal tumorigenesis JO - Cancer Res VL - 67 UR - https://doi.org/10.1158/0008-5472.CAN-06-2559 DO - 10.1158/0008-5472.CAN-06-2559 ID - Labbe2007 ER - TY - JOUR AU - Morrison, B. J. AU - Schmidt, C. W. AU - Lakhani, S. R. AU - Reynolds, B. A. AU - Lopez, J. A. PY - 2008 DA - 2008// TI - Breast cancer stem cells: implications for therapy of breast cancer JO - Breast Cancer Res VL - 10 UR - https://doi.org/10.1186/bcr2111 DO - 10.1186/bcr2111 ID - Morrison2008 ER - TY - JOUR AU - Cardiff, R. D. AU - Sinn, E. AU - Muller, W. AU - Leder, P. PY - 1991 DA - 1991// TI - Transgenic oncogene mice. Tumor phenotype predicts genotype JO - Am J Pathol VL - 139 ID - Cardiff1991 ER - TY - JOUR AU - Rosner, A. AU - Miyoshi, K. AU - Landesman-Bollag, E. AU - Xu, X. AU - Seldin, D. C. AU - Moser, A. R. AU - MacLeod, C. L. AU - Shyamala, G. AU - Gillgrass, A. E. AU - Cardiff, R. D. PY - 2002 DA - 2002// TI - Pathway pathology: histological differences between ErbB/Ras and Wnt pathway transgenic mammary tumors JO - Am J Pathol VL - 161 UR - https://doi.org/10.1016/S0002-9440(10)64269-1 DO - 10.1016/S0002-9440(10)64269-1 ID - Rosner2002 ER - TY - JOUR AU - Alonso, L. AU - Fuchs, E. PY - 2003 DA - 2003// TI - Stem cells in the skin: waste not, Wnt not JO - Genes Dev VL - 17 UR - https://doi.org/10.1101/gad.1086903 DO - 10.1101/gad.1086903 ID - Alonso2003 ER - TY - JOUR AU - Reya, T. AU - Clevers, H. PY - 2005 DA - 2005// TI - Wnt signalling in stem cells and cancer JO - Nature VL - 434 UR - https://doi.org/10.1038/nature03319 DO - 10.1038/nature03319 ID - Reya2005 ER - TY - JOUR AU - Tang, B. AU - Yoo, N. AU - Vu, M. AU - Mamura, M. AU - Nam, J. S. AU - Ooshima, A. AU - Du, Z. AU - Desprez, P. Y. AU - Anver, M. R. AU - Michalowska, A. M. AU - Shih, J. AU - Parks, W. T. AU - Wakefield, L. M. PY - 2007 DA - 2007// TI - Transforming growth factor-beta can suppress tumorigenesis through effects on the putative cancer stem or early progenitor cell and committed progeny in a breast cancer xenograft model JO - Cancer Res VL - 67 UR - https://doi.org/10.1158/0008-5472.CAN-07-0982 DO - 10.1158/0008-5472.CAN-07-0982 ID - Tang2007 ER - TY - JOUR AU - Boulanger, C. A. AU - Wagner, K. U. AU - Smith, G. H. PY - 2005 DA - 2005// TI - Parity-induced mouse mammary epithelial cells are pluripotent, self-renewing and sensitive to TGF-beta1 expression JO - Oncogene VL - 24 UR - https://doi.org/10.1038/sj.onc.1208185 DO - 10.1038/sj.onc.1208185 ID - Boulanger2005 ER - TY - JOUR AU - Kordon, E. C. AU - McKnight, R. A. AU - Jhappan, C. AU - Hennighausen, L. AU - Merlino, G. AU - Smith, G. H. PY - 1995 DA - 1995// TI - Ectopic TGF beta 1 expression in the secretory mammary epithelium induces early senescence of the epithelial stem cell population JO - Dev Biol VL - 168 UR - https://doi.org/10.1006/dbio.1995.1060 DO - 10.1006/dbio.1995.1060 ID - Kordon1995 ER -