Table 5 Other agents under investigation in metastatic breast cancer
Agent | Class of agent | Stage of development |
|---|---|---|
Tipifarnib | Farnesyl transferase inhibitor Inhibits Ras activation | II |
Deforolimus | mTOR inhibitor | II |
Everolimus | mTOR inhibitor | II |
Sirolimus | mTOR inhibitor | I |
Temsirolimus | mTOR inhibitor | Discontinued |
KU-59436 | PARP inhibitor | II |
BSI-2011 | PARP inhibitor | II |
AG-14699 | PARP inhibitor | II |