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Table 3 Multivariate Cox regression of lymphocyte-specific kinase metagene and standard parameters among estrogen receptor-positive HER2-positive tumors

From: T-cell metagene predicts a favorable prognosis in estrogen receptor-negative and HER2-positive breast cancers

Parameter   n 1 a n 2 a P valueb Hazard ratio 95% confidence interval
Lymphocyte-specific kinase metagene Low vs. high 21 16 0.011 4.17 1.38 to 12.6
Lymph node status LNN vs. N1 24 13 0.438 0.69 0.27 to 1.77
Age >50 years vs. ≤ 50 years 18 19 0.558 1.38 0.47 to 4.09
Pathological grading Poor vs. well/intermediate 19 18 0.097 2.27 0.86 to 5.99
Tumor size >2 cm vs. ≤ 2 cm 15 22 0.405 1.63 0.52 to 5.12
  1. aComplete information on all parameters was available for 37 estrogen receptor-positive human epidermal growth factor receptor 2 (HER2)-positive samples. bSignificant values presented in bold.