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Table 2 Multivariate Cox regression of lymphocyte-specific kinase metagene and standard parameters among estrogen receptor-negative tumors

From: T-cell metagene predicts a favorable prognosis in estrogen receptor-negative and HER2-positive breast cancers

Parameter Stratification n 1 a n 2 a P valueb Hazard ratio 95% confidence interval
Lymphocyte-specific kinase metagene Low vs. high 60 64 0.017 2.16 1.15 to 4.03
Lymph node status LNN vs. N1 89 35 0.059 1.84 0.98 to 3.47
Age >50 years vs. ≤ 50 years 71 53 0.91 0.97 0.53 to 1.78
Pathological grading Poor vs. well/intermediate 83 41 0.97 1.01 0.53 to 1.95
Tumor size >2 cm vs. ≤ 2 cm 76 48 0.078 1.85 0.93 to 3.66
Human epidermal growth factor receptor 2 status Positive vs. negative 45 79 0.78 1.09 0.58 to 2.05
  1. aComplete information on all parameters was available for 124 estrogen receptor-negative samples. bSignificant values presented in bold.