Figure 2
From: Prediction of paclitaxel sensitivity by CDK1 and CDK2 activity in human breast cancer cells
Cyclin-dependent kinase expression and specific activity levels and cyclin expression in breast cancer cell lines. Cells were treated with 100 nM paclitaxel for 0, 24, 48, or 72 hours, after which they were harvested, lysed, and assayed. (a) Cyclin-dependent kinase (CDK) 1 (left) and CDK2 (right) specific activity. (b) Cyclin B expression. (c) Cyclin E expression. U, units.