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Table 6 Cox multivariate regression analyses of selected variables in relation to disease-free survival and overall survival

From: Determination of HER2 phosphorylation at tyrosine 1221/1222 improves prediction of poor survival for breast cancer patients with hormone receptor-positive tumors

Variable Disease-free survival Overall survival
  P value Relative risk (95% CI) P value Relative risk (95% CI)
Tumor grade 0.544 1.17 (0.71 to 1.92) 0.187 1.35 (0.87 to 2.09)
Tumor size 0.018 1.76 (1.10 to 2.80) 0.060 1.48 (0.98 to 2.21)
Nodal status <0.0001 3.11 (1.90 to 5.11) 0.0001 2.29 (1.50 to 3.49)
HER2 0.097 1.84 (0.90 to 3.78) 0.574 1.22 (0.62 to 2.40)
pHER2 0.009 2.14 (1.21 to 3.78) 0.005 2.10 (1.25 to 3.52)
  1. Variables were included in the following categories: tumor grade (1 and 2 vs. 3), tumor size (<25 mm vs. ≥ 25 mm), nodal status (0 vs. ≥ 1), HER2 (negative vs. positive), pHER2 (negative and weak vs. strong). 95% CI, 95% confidence interval. Bold data represent significant values.