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Table 7 Top 20 gene sets enriched in grade III-associated stroma

From: Gene expression profiling of the tumor microenvironment during breast cancer progression

Name Size (number of genes) Normalized enrichment score False discovery rate q value
CELLULAR_DEFENSE_RESPONSE 52 2.31 0
IMMUNE_RESPONSE 220 2.17 0
IMMUNE_SYSTEM_PROCESS 312 2.16 0
T_CELL_ACTIVATION 42 2.14 0
LEUKOCYTE_ACTIVATION 67 2.09 0
JAK_STAT_CASCADE 28 2.05 6.82 × 10-4
LYMPHOCYTE_ACTIVATION 59 2.05 5.85 × 10-4
CELL_ACTIVATION 73 2.04 5.12 × 10-4
M_PHASE_OF_MITOTIC_CELL_CYCLE 78 2.04 4.55 × 10-4
RESPONSE_TO_VIRUS 48 2.04 5.12 × 10-4
SPINDLE 39 2.03 5.60 × 10-4
MITOSIS 75 2.02 5.99 × 10-4
INTERLEUKIN_RECEPTOR_ACTIVITY 20 2.01 6.33 × 10-4
POSITIVE_REGULATION_OF_IMMUNE_RESPONSE 28 2.00 7.35 × 10-4
REGULATION_OF_IMMUNE_SYSTEM_PROCESS 66 1.99 7.54 × 10-4
POSITIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS 50 1.99 7.07 × 10-4
RESPONSE_TO_BIOTIC_STIMULUS 112 1.99 6.65 × 10-4
REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_CASCADE 89 1.99 6.85 × 10-4
MRNA_PROCESSING_GO_0006397 67 1.97 0.001135
RESPONSE_TO_OTHER_ORGANISM 76 1.96 0.001282