Table 7 Top 20 gene sets enriched in grade III-associated stroma
From: Gene expression profiling of the tumor microenvironment during breast cancer progression
Name | Size (number of genes) | Normalized enrichment score | False discovery rate q value |
|---|---|---|---|
CELLULAR_DEFENSE_RESPONSE | 52 | 2.31 | 0 |
IMMUNE_RESPONSE | 220 | 2.17 | 0 |
IMMUNE_SYSTEM_PROCESS | 312 | 2.16 | 0 |
T_CELL_ACTIVATION | 42 | 2.14 | 0 |
LEUKOCYTE_ACTIVATION | 67 | 2.09 | 0 |
JAK_STAT_CASCADE | 28 | 2.05 | 6.82 × 10-4 |
LYMPHOCYTE_ACTIVATION | 59 | 2.05 | 5.85 × 10-4 |
CELL_ACTIVATION | 73 | 2.04 | 5.12 × 10-4 |
M_PHASE_OF_MITOTIC_CELL_CYCLE | 78 | 2.04 | 4.55 × 10-4 |
RESPONSE_TO_VIRUS | 48 | 2.04 | 5.12 × 10-4 |
SPINDLE | 39 | 2.03 | 5.60 × 10-4 |
MITOSIS | 75 | 2.02 | 5.99 × 10-4 |
INTERLEUKIN_RECEPTOR_ACTIVITY | 20 | 2.01 | 6.33 × 10-4 |
POSITIVE_REGULATION_OF_IMMUNE_RESPONSE | 28 | 2.00 | 7.35 × 10-4 |
REGULATION_OF_IMMUNE_SYSTEM_PROCESS | 66 | 1.99 | 7.54 × 10-4 |
POSITIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS | 50 | 1.99 | 7.07 × 10-4 |
RESPONSE_TO_BIOTIC_STIMULUS | 112 | 1.99 | 6.65 × 10-4 |
REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_CASCADE | 89 | 1.99 | 6.85 × 10-4 |
MRNA_PROCESSING_GO_0006397 | 67 | 1.97 | 0.001135 |
RESPONSE_TO_OTHER_ORGANISM | 76 | 1.96 | 0.001282 |