Skip to main content

Advertisement

Table 6 Top 50 genes differentially expressed in invasive stroma compared to in situ stroma

From: Gene expression profiling of the tumor microenvironment during breast cancer progression

Probe set Log2 (fold change) Adjusted P value Gene description
Hs2.434299.1.S1_3p_at 1.61 8.58 × 10-3 -
g13027795_3p_s_at 1.45 1.74 × 10-2 MMP11 – matrix metallopeptidase 11 (stromelysin 3)
Hs.50081.1.S1_3p_a_at 1.36 5.47 × 10-3 KIAA1199 – KIAA1199
g11641276_3p_s_at 1.24 3.71 × 10-2 PDE4DIP – phosphodiesterase 4D interacting protein (myomegalin)
Hs.169517.0.S1_3p_a_at 1.16 5.72 × 10-3 ALDH1B1 – aldehyde dehydrogenase 1 family, member B1
Hs.98523.0.A1_3p_at 1.13 5.32 × 10-3 FAT3 – FAT tumor suppressor homolog 3 (Drosophila)
g10938018_3p_at 1.04 1.74 × 10-2 EPYC – epiphycan
Hs2.350890.1.S1_3p_s_at 1.03 3.72 × 10-2 GABRB2 – gamma-aminobutyric acid (GABA) A receptor, beta 2
g4507922_3p_at 0.98 1.70 × 10-2 WISP2 – WNT1 inducible signaling pathway protein 2
g11342665_3p_at 0.98 4.53 × 10-2 MMP2 – matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72 kDa type IV collagenase)
g13124890_3p_a_at 0.93 3.28 × 10-2 GALNT1 – UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)
Hs.98523.0.A1_3p_x_at 0.87 3.15 × 10-2 FAT3 – FAT tumor suppressor homolog 3 (Drosophila)
Hs.238532.0.A1_3p_at 0.76 3.71 × 10-2 GALNTL2 – UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2
Hs.42927.0.S1_3p_at 0.75 3.39 × 10-2 ANTXR1 – anthrax toxin receptor 1
Hs2.359399.1.S1_3p_at 0.74 3.71 × 10-2 LOC285758 – hypothetical protein LOC285758
Hs.235795.0.A1_3p_at 0.74 1.38 × 10-2 -
Hs2.46679.2.S1_3p_s_at 0.66 2.11 × 10-3 -
g469044_3p_a_at 0.60 3.22 × 10-2 CNTN1 – contactin 1
g4758607_3p_at 0.53 1.20 × 10-2 -
Hs.288553.0.S1_3p_s_at 0.52 2.82 × 10-2 -
200661_3p_at 0.51 4.16 × 10-2 CTSA – cathepsin A
Hs.2399.1.S1_3p_s_at 0.51 4.48 × 10-2 MMP14 – matrix metallopeptidase 14 (membrane-inserted)
Hs.98183.0.A1_3p_at 0.48 8.58 × 10-3 RSPO4 – R-spondin family, member 4
208756_3p_at 0.48 2.28 × 10-2 EIF3I – eukaryotic translation initiation factor 3, subunit I
Hs.162647.0.S1_3p_at 0.48 2.69 × 10-2 DKFZP547L112 – hypothetical protein DKFZp547L112
Hs.22968.0.S1_3p_a_at -2.00 8.37 × 10-6 FLT1 – fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
g11545907_3p_at -2.03 2.68 × 10-5 ELTD1 – EGF, latrophilin and seven transmembrane domain containing 1
g5032094_3p_at -2.03 3.64 × 10-7 SLCO2A1 – solute carrier organic anion transporter family, member 2A1
Hs.8707.0.S1_3p_at -2.07 1.29 × 10-5 HECW2 – HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
Hs.134970.0.S1_3p_a_at -2.07 6.66 × 10-3 KIF26A – kinesin family member 26A
Hs2.420404.1.S1_3p_at -2.08 7.70 × 10-6 PELO – pelota homolog (Drosophila)
g4504850_3p_a_at -2.11 3.62 × 10-2 KCNK5 – potassium channel, subfamily K, member 5
Hs.288681.0.S1_3p_at -2.13 4.98 × 10-4 THSD7A – thrombospondin, type I, domain containing 7A
g4557546_3p_at -2.15 1.58 × 10-3 EDNRB – endothelin receptor type B
g11321596_3p_at -2.19 1.64 × 10-3 KDR – kinase insert domain receptor (a type III receptor tyrosine kinase)
Hs.124675.0.A1_3p_at -2.21 2.21 × 10-4 GIMAP7 – GTPase, IMAP family member 7
Hs.211388.0.S1_3p_at -2.24 5.72 × 10-3 RUNDC3B – RUN domain containing 3B
g4885556_3p_at -2.25 2.13 × 10-3 PODXL – podocalyxin-like
Hs.26530.0.S2_3p_at -2.30 1.60 × 10-3 SDPR – serum deprivation response (phosphatidylserine binding protein)
g13518036_3p_a_at -2.41 7.19 × 10-3 MATN2 – matrilin 2
Hs.102415.0.S1_3p_at -2.43 2.67 × 10-8 EMCN – endomucin
Hs.61935.0.S1_3p_at -2.45 2.68 × 10-5 PCDH17 – protocadherin 17
g8547214_3p_at -2.46 3.74 × 10-5 EMCN – endomucin
g4520327_3p_at -2.48 2.67 × 10-3 IL33 – interleukin 33
Hs.10587.0.S1_3p_at -2.66 2.29 × 10-3 DMN – desmuslin
g3644039_3p_a_at -2.67 1.43 × 10-2 TP63 – tumor protein p63
Hs.78344.1.S2_3p_a_at -2.87 2.13 × 10-3 MYH11 – myosin, heavy chain 11, smooth muscle
g6580814_3p_s_at -2.93 8.90 × 10-5 INMT – indolethylamine N-methyltransferase
Hs.173560.0.S1_3p_at -2.94 3.58 × 10-2 ODZ2 – odz, odd Oz/ten-m homolog 2 (Drosophila)
g4506870_3p_at -3.23 1.80 × 10-3 SELE – selectin E (endothelial adhesion molecule 1)