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Table 4 Top 50 genes differentially expressed in tumor epithelium

From: Gene expression profiling of the tumor microenvironment during breast cancer progression

Probe set DICS IDC Gene description
g5174662_3p_at 5.3 4.0 S100P – S100 calcium binding protein P
g11993936_3p_s_at 4.5 3.4 CYB561 – cytochrome b-561
g7415720_3p_a_at 4.0 3.0 SCD – stearoyl-CoA desaturase (delta-9-desaturase)
Hs.75319.0.S3_3p_at 3.0 3.8 RRM2 – ribonucleotide reductase M2 polypeptide
Hs.106552.0.S3_3p_s_at 4.2 2.3 CNTNAP2 – contactin associated protein-like 2
g12803628_3p_at 3.7 2.6 HIST1H1C – histone cluster 1, H1c
g5031780_3p_at 4.0 2.3 IFI27 – interferon, alpha-inducible protein 27
Hs.180779.1.S1_3p_at 3.1 3.0 HIST1H2BD – histone cluster 1, H2bd
Hs.184572.0.S2_3p_at 2.7 3.3 CDC2 – cell division cycle 2, G1 to S and G2 to M
Hs.223025.0.S2_3p_a_at 2.6 3.4 RAB31 – RAB31, member RAS oncogene family
g12804874_3p_a_at 2.8 3.1 RRM2 – ribonucleotide reductase M2 polypeptide
Hs.239884.0.S1_3p_x_at 3.5 2.4 HIST1H2BC – histone cluster 1, H2bc
g7661973_3p_at 2.7 3.1 MELK – maternal embryonic leucine zipper kinase
g13259549_3p_at 3.2 2.4 IFI6 – interferon, alpha-inducible protein 6
g4504584_3p_at 3.5 2.0 IFIT1 – interferon-induced protein with tetratricopeptide repeats 1
Hs.155956.0.S1_3p_at 2.6 2.8 NAT1 – N-acetyltransferase 1 (arylamine N-acetyltransferase)
Hs.152677.0.S1_3p_at 3.1 2.3 DHRS2 – dehydrogenase/reductase (SDR family) member 2
Hs.239884.0.S1_3p_at 3.3 2.1 HIST1H2BC – histone cluster 1, H2bc
g5803130_3p_a_at 2.2 3.2 RAB31 – RAB31, member RAS oncogene family
g13699814_3p_s_at 2.7 2.7 CYP2B6 – cytochrome P450, family 2, subfamily B, polypeptide 6
g9963780_3p_a_at 2.2 3.2 RAB31 – RAB31, member RAS oncogene family
Hs.72472.0.A1_3p_at 2.3 2.9 -
g13477106_3p_s_at 3.3 1.8 CEACAM6 – carcinoembryonic antigen-related cell adhesion molecule 6 (nonspecific cross-reacting antigen)
Hs.133342.0.S1_3p_x_at 2.9 2.2 GPC1 – glypican 1
Hs.325335.1.S1_3p_at 2.6 2.5 CAPN13 – calpain 13
Hs.34853.0.S2_3p_at -3.5 -4.0 ID4 – inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
g3387766_3p_a_at -3.9 -3.6 GPM6B – glycoprotein M6B
Hs.10587.0.S1_3p_at -3.2 -4.3 DMN – desmuslin
Hs2.348883.1.S1_3p_s_at -3.9 -3.6 FOXC1 – forkhead box C1
g4758521_3p_at -4.9 -2.7 SPARCL1 – SPARC-like 1 (mast9, hevin)
g11037715_3p_x_at -3.9 -3.7 ROPN1 – ropporin, rhophilin associated protein 1
g4504914_3p_at -3.9 -3.8 KRT15 – keratin 15
Hs.82101.0.S3_3p_at -3.7 -4.0 PHLDA1 – pleckstrin homology-like domain, family A, member 1
Hs.149356.0.S1_3p_at -3.8 -3.9 LOC728264 – hypothetical protein LOC728264
g4506856_3p_s_at -3.3 -4.6 CX3CL1 – chemokine (C-X3-C motif) ligand 1
g4506516_3p_at -3.9 -4.1 RGS2 – regulator of G-protein signaling 2, 24 kDa
g7657105_3p_at -4.2 -4.0 GABRP – gamma-aminobutyric acid (GABA) A receptor, pi
Hs.25956.0.S1_3p_at -4.1 -4.4 SOSTDC1 – sclerostin domain containing 1
Hs.153961.2.S2_3p_at -4.6 -3.9 BOC – Boc homolog (mouse)
g11991655_3p_at -4.5 -4.2 C2orf40 – chromosome 2 open reading frame 40
Hs.288850.0.S1_3p_at -4.1 -4.7 PHLDA1 – pleckstrin homology-like domain, family A, member 1
g7662650_3p_at -5.1 -3.7 C13orf15 – chromosome 13 open reading frame 15
g4557694_3p_a_at -4.5 -4.5 KIT – v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Hs.127428.2.S2_3p_a_at -4.3 -4.9 HOXA9 – homeobox A9
g6005949_3p_at -4.4 -4.8 WIF1 – WNT inhibitory factor 1
Hs.34853.0.S3_3p_at -4.8 -4.5 ID4 – inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
g4559274_3p_a_at -4.1 -5.3 ELF5 – E74-like factor 5 (ets domain transcription factor)
g8400731_3p_a_at -4.4 -5.2 SFRP1 – secreted frizzled-related protein 1
g5032314_3p_a_at -4.9 -4.9 DMD – dystrophin (muscular dystrophy, Duchenne and Becker types)
g6005714_3p_at -4.7 -5.6 SLC6A14 – solute carrier family 6 (amino acid transporter), member 14
  1. Ductal carcinoma in situ (DCIS) and invasive ductal carcinoma (IDC) data presented as log2(fold changes) relative to normal epithelium.