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Table 3 Top 20 gene ontology terms enriched in tumor epithelium and stroma

From: Gene expression profiling of the tumor microenvironment during breast cancer progression

Name Size (number of genes) Normalized enrichment score False discovery rate q value
Epithelium    
   SPINDLE 39 2.33 0
   CHROMOSOME_SEGREGATION 28 2.15 0
   CELL_CYCLE_PROCESS 180 2.12 0
MICROTUBULE_CYTOSKELETON_ORGANIZATION_AND_BIOGENESIS 34 2.11 0
   CHROMOSOME__PERICENTRIC_REGION 27 2.11 0
   MICROTUBULE_CYTOSKELETON 142 2.11 0
   PROTEASOME_COMPLEX 22 2.09 1.40 × 10-4
   CONDENSED_CHROMOSOME 30 2.06 2.48 × 10-4
   M_PHASE 105 2.06 2.20 × 10-4
   NUCLEAR_ENVELOPE 71 2.05 1.98 × 10-4
   CELL_CYCLE_PHASE 157 2.05 1.80 × 10-4
   M_PHASE_OF_MITOTIC_CELL_CYCLE 78 2.04 2.49 × 10-4
   CHROMOSOME 115 2.03 2.30 × 10-4
   CYTOSKELETAL_PART 221 2.03 2.14 × 10-4
   MITOSIS 75 2.02 2.66 × 10-4
   MICROTUBULE 32 1.99 2.49 × 10-4
   MITOTIC_CELL_CYCLE 139 1.99 2.35 × 10-4
   CELL_CYCLE_CHECKPOINT_GO_0000075 45 1.98 2.21 × 10-4
   SPINDLE_MICROTUBULE 16 1.97 2.63 × 10-4
   DNA_REPAIR 120 1.94 6.01 × 10-4
   STRUCTURAL_CONSTITUENT_OF_RIBOSOME 74 -3.09 0
Stroma    
EXTRACELLULAR_MATRIX_STRUCTURAL_CONSTITUENT 25 2.12 0
   COLLAGEN 23 2.07 0.001566
   METALLOENDOPEPTIDASE_ACTIVITY 26 2.06 0.001044
   EXTRACELLULAR_MATRIX 94 1.99 0.001568
   PROTEINACEOUS_EXTRACELLULAR_MATRIX 93 1.97 0.002923
   EXTRACELLULAR_MATRIX_PART 54 1.91 0.007826
   SPINDLE 39 1.89 0.008346
   METALLOPEPTIDASE_ACTIVITY 45 1.82 0.027006
   SKELETAL_DEVELOPMENT 99 1.80 0.032482
   STRUCTURAL_CONSTITUENT_OF_RIBOSOME 74 -3.04 0