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Figure 3 | Breast Cancer Research

Figure 3

From: Tamoxifen induces pleiotrophic changes in mammary stroma resulting in extracellular matrix that suppresses transformed phenotypes

Figure 3

Tamoxifen extracellular matrix (ECM) recruits fewer macrophages than control ECM in a transwell filter assay. (a) Photomicrographs of transwell filters showing that J774 macrophage cells are less chemotactic towards tamoxifen ECM compared with control ECM. 100× magnification. (b) Quantitation of J774 cell motility demonstrates significantly reduced chemotaxis towards tamoxifen ECM. *p = 0.003.

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