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Figure 3 | Breast Cancer Research

Figure 3

From: Phosphoinositide 3-kinase targeting by the β galactoside binding protein cytokine negates akt gene expression and leads aggressive breast cancer cells to apoptotic death

Figure 3

Extracellular signal-regulated kinase (ERK) levels and Akt mRNA levels as expression of endogenous and enforced mitogenic input in BT474, SKBR3, naïve MCF10A, MCF10ACTx and MCF10AV12Ras cells. Phosphorylated ERK, total ERK and Akt mRNA assessed in parallel at 48 h or 72 h (SKBR3) during mitogenic expansion. The data are from time scale assessments using equal amounts of protein and equal amounts of RNA and equal exposure times in separate gels due to space limitations when electrophoresing five different cell lines. Repetitions of the experiments gave identical results.

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