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Table 2 Genes modulated as a consequence of CD146 downmodulation

From: CD146 expression is associated with a poor prognosis in human breast tumors and with enhanced motility in breast cancer cell lines

Symbol Accession number Fold change P value (t test)
DNA microarray
   LIPG [GenBank:NM_006033] -6.75 0.02749
   MCAM [GenBank:NM_006500] -3.61 0.00084
   FPR1 [GenBank:NM_002029] -2.88 0.03159
   CYP1B1 [GenBank:NM_000104] -2.73 0.03208
   FN1 [GenBank:NM_212475] -2.48 0.00657
   SORCS2 [GenBank:NM_020777] -2.17 0.0314
   FLJ20160 [GenBank:NM_017694] -1.74 0.01431
   LTBP1 [GenBank:NM_206943] -1.72 0.03606
   HES1 [GenBank:NM_005524] -1.7 0.04315
   AIM1 [GenBank:NM_001624] -1.63 0.00758
   MFAP2 [GenBank:NM_002403] -1.58 0.04437
   HIPK2 [GenBank:NM_022740] -1.55 0.00781
   CALD1 [GenBank:NM_033138] -1.51 0.0113
   NAV1 [GenBank:NM_020443] -1.5 0.00481
   NFIC [GenBank:NM_005597] -1.5 0.0275
   TGFBI [GenBank:NM_000660] -1.85* 0.03459
   TRIM59 [GenBank:NM_173084] -1.76* 0.01626
   NFAT5 [GenBank:NM_138714] -1.51* 0.04496
   APCDD1L [GenBank:NM_153360] -2.38** 0.01035
   GARNL4 [GenBank:NM_001100398] -1.96** 0.04209
   PCMTD1 [GenBank:NM_052937] -1.59** 0.0362
Multiplex quantitative RT-PCR
   KALRN [GenBank:NM_003947] -10 0.02973
   PREX1 [GenBank:NM_020820] -8.93 0.01711
   VAV1 [GenBank:NM_005428] -7.94 0.00688
   FGD4 [GenBank:NM_139241] -4.63 0.00318
   RHOV [GenBank:NM_133639] -4.03 0.03116
   CCL5 [GenBank:NM_002985] -3.88 0.00536
   ITGB3 [GenBank:NM_000212] -3.61 0.00187
   CXCL16 [GenBank:NM_022059] -2.92 0.00252
   THBS1 [GenBank:NM_003246] -2.66 0.01279
   CXCR4 [GenBank:NM_001008540] -2.21 0.00259
   ITGB4 [GenBank:NM_001005731] -2.15 0.01068
   CD44 [GenBank:NM_000610] -1.92 0.00141
   ITGA2 [GenBank:NM_002203] -1.86 0.00191
   ROCK2 [GenBank:NM_004850] -1,80 0.00004
   ITGA6 [GenBank:NM_000210] -1.63 0.00274
   VIM [GenBank:NM_003380] -1.45*** 0.04761
   ARHGEF11 [GenBank:NM_198236] 1.67 0.00288
   BCL7A [GenBank:NM_001024808] 1.69 0.02473
   DEF6 [GenBank:NM_022047] 2.05 0.00946
   TNK2 [GenBank:NM_005781] 2.18 0.00222
   CXCL10 [GenBank:NM_001565] 2.51 0.03645
  1. *Not validated by quantitative RT-PCR. **Quantitative RT-PCR not available.***Observed only with the TI6194 cell line.