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Table 1 Distribution of prognostic phenotypes in 899 patients from the POSH cohort according to outcome

From: The influence of genetic variation in 30 selected genes on the clinical characteristics of early onset breast cancer

Outcome Number DDFSa ER statusb Tumour gradeb Diameter (cM) pN stageb
    Negative Positive 1 2 3   1 0
Deceased 102 1.48 (0.00 to 4.77) 53 (53.0) 47 (47.0) 2 (2.0) 19 (19.2) 78 (78.8) 3.67 70 (76.9) 21 (23.1)
Distant relapse 55 1.90 (0.00 to 4.62) 18 (32.7) 37 (67.3) 2 (3.8) 18 (34.0) 33 (62.0) 3.00 38 (74.5) 13 (25.5)
Disease free 742 2.61 (0.05 to 6.69) 202 (27.6) 531 (72.4) 60 (8.2) 269 (36.8) 402 (55.0) 2.58 352 (48.4) 376 (51.6)
Total 899 2.44 (0.00 to 6.69) 273 (30.7) 615 (69.3) 64 (7.2) 306 (34.7) 513 (58.1) 2.72 460 (52.9) 410 (47.1)
  1. aDistant disease free survival times in years and (range). bNumbers outside parenthesis represent counts while those inside are percentages of the total number in each outcome group. DDFS, distant disease-free survival; ER, ostrogen receptor; pN, pathological nodal; POSH, Prospective study of Outcomes in Sporadic versus Hereditary breast cancer.