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Table 2 Association of age at menarche with tumor-defined characteristics of breast cancer

From: The influence of menstrual risk factors on tumor characteristics and survival in postmenopausal breast cancer

 

Age at menarche, years

 

Tumor characteristic

≤11

> 11 and ≤13

> 13 and ≤14

> 14

P valuea

Tumor size

     

   1–10 mm

47 (28)

258 (26)

183 (27)

153 (29)

 

   11–20 mm

76 (46)

414 (43)

302 (44)

250 (47)

 

   ≥21 mm

43 (26)

304 (31)

199 (29)

129 (24)

0.188

Grade

     

   Low

12 (10)

98 (15)

66 (14)

71 (20)

 

   Medium

50 (44)

270 (40)

214 (46)

136 (39)

 

   High

52 (46)

304 (45)

188 (40)

141 (40)

0.037

ER status

     

   Positive

91 (73)

145 (20)

113 (23)

302 (79)

 

   Negative

34 (27)

564 (80)

381 (77)

78 (21)

0.309

PR status

     

   Positive

84 (69)

224 (32)

181 (37)

252 (68)

 

   Negative

38 (31)

473 (68)

305 (63)

121 (32)

0.250

Lymph node involvement

     

   Absent

104 (63)

630 (66)

456 (68)

374 (72)

 

   Present

60 (37)

329 (34)

217 (32)

146 (28)

0.052

Histology

     

   Ductal

124 (75)

692 (71)

503 (73)

383 (72)

 

   Lobular

24 (14)

118 (12)

78 (11)

62 (12)

 

   All other

18 (11)

165 (17)

108 (16)

87 (16)

0.509

  1. aPearson chi-square tests of association between groups. ER, estrogen receptor; PR, progesterone receptor.