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Table 2 Association of age at menarche with tumor-defined characteristics of breast cancer

From: The influence of menstrual risk factors on tumor characteristics and survival in postmenopausal breast cancer

  Age at menarche, years  
Tumor characteristic ≤11 > 11 and ≤13 > 13 and ≤14 > 14 P valuea
Tumor size      
   1–10 mm 47 (28) 258 (26) 183 (27) 153 (29)  
   11–20 mm 76 (46) 414 (43) 302 (44) 250 (47)  
   ≥21 mm 43 (26) 304 (31) 199 (29) 129 (24) 0.188
Grade      
   Low 12 (10) 98 (15) 66 (14) 71 (20)  
   Medium 50 (44) 270 (40) 214 (46) 136 (39)  
   High 52 (46) 304 (45) 188 (40) 141 (40) 0.037
ER status      
   Positive 91 (73) 145 (20) 113 (23) 302 (79)  
   Negative 34 (27) 564 (80) 381 (77) 78 (21) 0.309
PR status      
   Positive 84 (69) 224 (32) 181 (37) 252 (68)  
   Negative 38 (31) 473 (68) 305 (63) 121 (32) 0.250
Lymph node involvement      
   Absent 104 (63) 630 (66) 456 (68) 374 (72)  
   Present 60 (37) 329 (34) 217 (32) 146 (28) 0.052
Histology      
   Ductal 124 (75) 692 (71) 503 (73) 383 (72)  
   Lobular 24 (14) 118 (12) 78 (11) 62 (12)  
   All other 18 (11) 165 (17) 108 (16) 87 (16) 0.509
  1. aPearson chi-square tests of association between groups. ER, estrogen receptor; PR, progesterone receptor.