TY - JOUR AU - Nicholson, R. I. AU - Hutcheson, I. R. AU - Britton, D. AU - Knowlden, J. M. AU - Jones, H. E. AU - Harper, M. E. AU - Hiscox, S. E. AU - Barrow, D. AU - Gee, J. M. PY - 2005 DA - 2005// TI - Growth factor signalling networks in breast cancer and resistance to endocrine agents: new therapeutic strategies JO - J Steroid Biochem Mol Biol VL - 93 UR - https://doi.org/10.1016/j.jsbmb.2004.12.006 DO - 10.1016/j.jsbmb.2004.12.006 ID - Nicholson2005 ER - TY - JOUR AU - Gee, J. M. AU - Shaw, V. E. AU - Hiscox, S. E. AU - McClelland, R. A. AU - Rushmere, N. K. AU - Nicholson, R. I. PY - 2006 DA - 2006// TI - Deciphering antihormone-induced compensatory mechanisms in breast cancer and their therapeutic implications JO - Endocrine-related cancer VL - 13 UR - https://doi.org/10.1677/erc.1.01274 DO - 10.1677/erc.1.01274 ID - Gee2006 ER - TY - JOUR AU - Frasor, J. AU - Stossi, F. AU - Danes, J. M. AU - Komm, B. AU - Lyttle, C. R. AU - Katzenellenbogen, B. S. PY - 2004 DA - 2004// TI - Selective estrogen receptor modulators: discrimination of agonistic versus antagonistic activities by gene expression profiling in breast cancer cells JO - Cancer Res VL - 64 UR - https://doi.org/10.1158/0008-5472.CAN-03-3326 DO - 10.1158/0008-5472.CAN-03-3326 ID - Frasor2004 ER - TY - JOUR AU - Nicholson, R. I. AU - Hutcheson, I. R. AU - Hiscox, S. E. AU - Knowlden, J. M. AU - Giles, M. AU - Barrow, D. AU - Gee, J. M. PY - 2005 DA - 2005// TI - Growth factor signalling and resistance to selective oestrogen receptor modulators and pure anti-oestrogens: the use of anti-growth factor therapies to treat or delay endocrine resistance in breast cancer JO - Endocr Relat Cancer VL - 12 UR - https://doi.org/10.1677/erc.1.00991 DO - 10.1677/erc.1.00991 ID - Nicholson2005 ER - TY - JOUR AU - Gee, J. M. AU - Harper, M. E. AU - Hutcheson, I. R. AU - Madden, T. A. AU - Barrow, D. AU - Knowlden, J. M. AU - McClelland, R. A. AU - Jordan, N. AU - Wakeling, A. E. AU - Nicholson, R. I. PY - 2003 DA - 2003// TI - The antiepidermal growth factor receptor agent gefitinib (ZD1839/Iressa) improves antihormone response and prevents development of resistance in breast cancer in vitro JO - Endocrinology VL - 144 UR - https://doi.org/10.1210/en.2003-0705 DO - 10.1210/en.2003-0705 ID - Gee2003 ER - TY - JOUR AU - Frasor, J. AU - Chang, E. C. AU - Komm, B. AU - Lin, C. Y. AU - Vega, V. B. AU - Liu, E. T. AU - Miller, L. D. AU - Smeds, J. AU - Bergh, J. AU - Katzenellenbogen, B. S. PY - 2006 DA - 2006// TI - Gene expression preferentially regulated by tamoxifen in breast cancer cells and correlations with clinical outcome JO - Cancer Research VL - 66 UR - https://doi.org/10.1158/0008-5472.CAN-05-4269 DO - 10.1158/0008-5472.CAN-05-4269 ID - Frasor2006 ER - TY - JOUR AU - Visram, H. AU - Greer, P. A. PY - 2006 DA - 2006// TI - 17beta-estradiol and tamoxifen stimulate rapid and transient ERK activationin MCF-7 cells via distinct signaling mechanisms JO - Cancer Biol Ther VL - 5 UR - https://doi.org/10.4161/cbt.5.12.3378 DO - 10.4161/cbt.5.12.3378 ID - Visram2006 ER - TY - JOUR AU - Cowell, L. N. AU - Graham, J. D. AU - Bouton, A. H. AU - Clarke, C. L. AU - O'Neill, G. M. PY - 2006 DA - 2006// TI - Tamoxifen treatment promotes phosphorylation of the adhesion molecules, p130Cas/BCAR1, FAK and Src, via an adhesion-dependent pathway JO - Oncogene VL - 25 UR - https://doi.org/10.1038/sj.onc.1209747 DO - 10.1038/sj.onc.1209747 ID - Cowell2006 ER - TY - JOUR AU - Acconcia, F. AU - Barnes, C. J. AU - Kumar, R. PY - 2006 DA - 2006// TI - Estrogen and tamoxifen induce cytoskeletal remodeling and migration in endometrial cancer cells JO - Endocrinology VL - 147 UR - https://doi.org/10.1210/en.2005-1293 DO - 10.1210/en.2005-1293 ID - Acconcia2006 ER - TY - JOUR AU - Hiscox, S. AU - Morgan, L. AU - Green, T. P. AU - Barrow, D. AU - Gee, J. AU - Nicholson, R. I. PY - 2006 DA - 2006// TI - Elevated Src activity promotes cellular invasion and motility in tamoxifen resistant breast cancer cells JO - Breast Cancer Res Treat VL - 97 UR - https://doi.org/10.1007/s10549-005-9120-9 DO - 10.1007/s10549-005-9120-9 ID - Hiscox2006 ER - TY - JOUR AU - Mendes, O. AU - Kim, H. T. AU - Lungu, G. AU - Stoica, G. PY - 2007 DA - 2007// TI - MMP2 role in breast cancer brain metastasis development and its regulation by TIMP2 and ERK1/2 JO - Clin Exp Metastasis VL - 24 UR - https://doi.org/10.1007/s10585-007-9071-0 DO - 10.1007/s10585-007-9071-0 ID - Mendes2007 ER - TY - JOUR AU - Feng, W. AU - Webb, P. AU - Nguyen, P. AU - Liu, X. AU - Li, J. AU - Karin, M. AU - Kushner, P. J. PY - 2001 DA - 2001// TI - Potentiation of estrogen receptor activation function 1 (AF-1) by Src/JNK through a serine 118-independent pathway JO - Mol Endocrinol VL - 15 UR - https://doi.org/10.1210/mend.15.1.0590 DO - 10.1210/mend.15.1.0590 ID - Feng2001 ER - TY - JOUR AU - Zhong, M. AU - Lu, Z. AU - Abbas, T. AU - Hornia, A. AU - Chatakondu, K. AU - Barile, N. AU - Kaplan, P. AU - Foster, D. A. PY - 2001 DA - 2001// TI - Novel tumor-promoting property of tamoxifen JO - Cell Growth Differ VL - 12 ID - Zhong2001 ER - TY - JOUR AU - Mege, R. M. AU - Gavard, J. AU - Lambert, M. PY - 2006 DA - 2006// TI - Regulation of cell-cell junctions by the cytoskeleton JO - Curr Opin Cell Biol VL - 18 UR - https://doi.org/10.1016/j.ceb.2006.08.004 DO - 10.1016/j.ceb.2006.08.004 ID - Mege2006 ER - TY - JOUR AU - Jeschke, U. AU - Mylonas, I. AU - Kuhn, C. AU - Shabani, N. AU - Kunert-Keil, C. AU - Schindlbeck, C. AU - Gerber, B. AU - Friese, K. AU - van Oort, I. M. AU - Tomita, K. AU - van Bokhoven, A. AU - Bussemakers, M. J. AU - Kiemeney, L. A. AU - Karthaus, H. F. AU - Witjes, J. A. AU - Schalken, J. A. PY - 2007 DA - 2007// TI - Expression of E-cadherin in human ductal breast cancer carcinoma in situ, invasive carcinomas, their lymph node metastases, their distant metastases, carcinomas with recurrence and in recurrence JO - Anticancer Res VL - 27 ID - Jeschke2007 ER - TY - JOUR AU - Kleiner, S. AU - Faisal, A. AU - Nagamine, Y. PY - 2007 DA - 2007// TI - Induction of uPA gene expression by the blockage of E-cadherin via Src- and Shc-dependent Erk signaling JO - Febs J VL - 274 UR - https://doi.org/10.1111/j.1742-4658.2006.05578.x DO - 10.1111/j.1742-4658.2006.05578.x ID - Kleiner2007 ER - TY - JOUR AU - Humar, B. AU - Fukuzawa, R. AU - Blair, V. AU - Dunbier, A. AU - More, H. AU - Charlton, A. AU - Yang, H. K. AU - Kim, W. H. AU - Reeve, A. E. AU - Martin, I. AU - Guilford, P. PY - 2007 DA - 2007// TI - Destabilized adhesion in the gastric proliferative zone and c-Src kinase activation mark the development of early diffuse gastric cancer JO - Cancer Res VL - 67 UR - https://doi.org/10.1158/0008-5472.CAN-06-3021 DO - 10.1158/0008-5472.CAN-06-3021 ID - Humar2007 ER - TY - JOUR AU - Fujita, N. AU - Jaye, D. L. AU - Kajita, M. AU - Geigerman, C. AU - Moreno, C. S. AU - Wade, P. A. PY - 2003 DA - 2003// TI - MTA3, a Mi-2/NuRD complex subunit, regulates an invasive growth pathway in breast cancer JO - Cell VL - 113 UR - https://doi.org/10.1016/S0092-8674(03)00234-4 DO - 10.1016/S0092-8674(03)00234-4 ID - Fujita2003 ER - TY - JOUR AU - Ree, A. H. AU - Bjornland, K. AU - Brunner, N. AU - Johansen, H. T. AU - Pedersen, K. B. AU - Aasen, A. O. AU - Fodstad, O. PY - 1998 DA - 1998// TI - Regulation of tissue-degrading factors and in vitro invasiveness in progression of breast cancer cells JO - Clin Exp Metastasis VL - 16 UR - https://doi.org/10.1023/A:1006584624061 DO - 10.1023/A:1006584624061 ID - Ree1998 ER - TY - JOUR AU - Lauffenburger, D. A. AU - Horwitz, A. F. PY - 1996 DA - 1996// TI - Cell migration: a physically integrated molecular process JO - Cell VL - 84 UR - https://doi.org/10.1016/S0092-8674(00)81280-5 DO - 10.1016/S0092-8674(00)81280-5 ID - Lauffenburger1996 ER - TY - JOUR AU - Hiscox, S. AU - Jordan, N. J. AU - Morgan, L. AU - Green, T. P. AU - Nicholson, R. I. PY - 2007 DA - 2007// TI - Src kinase promotes adhesion-independent activation of FAK and enhances cellular migration in tamoxifen-resistant breast cancer cells JO - Clin Exp Metastasis VL - 24 UR - https://doi.org/10.1007/s10585-007-9065-y DO - 10.1007/s10585-007-9065-y ID - Hiscox2007 ER - TY - JOUR AU - Fan, M. AU - Yan, P. S. AU - Hartman-Frey, C. AU - Chen, L. AU - Paik, H. AU - Oyer, S. L. AU - Salisbury, J. D. AU - Cheng, A. S. AU - Li, L. AU - Abbosh, P. H. AU - Huang, T. H. AU - Nephew, K. P. PY - 2006 DA - 2006// TI - Diverse gene expression and DNA methylation profiles correlate with differential adaptation of breast cancer cells to the antiestrogens tamoxifen and fulvestrant JO - Cancer Res VL - 66 UR - https://doi.org/10.1158/0008-5472.CAN-06-1666 DO - 10.1158/0008-5472.CAN-06-1666 ID - Fan2006 ER - TY - JOUR AU - Knowlden, J. M. AU - Hutcheson, I. R. AU - Jones, H. E. AU - Madden, T. AU - Gee, J. M. AU - Harper, M. E. AU - Barrow, D. AU - Wakeling, A. E. AU - Nicholson, R. I. PY - 2003 DA - 2003// TI - Elevated levels of epidermal growth factor receptor/c-erbB2 heterodimers mediate an autocrine growth regulatory pathway in tamoxifen-resistant MCF-7 cells JO - Endocrinology VL - 144 UR - https://doi.org/10.1210/en.2002-220620 DO - 10.1210/en.2002-220620 ID - Knowlden2003 ER - TY - JOUR PY - 2005 DA - 2005// TI - Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials JO - Lancet VL - 365 UR - https://doi.org/10.1016/S0140-6736(05)66544-0 DO - 10.1016/S0140-6736(05)66544-0 ID - ref24 ER - TY - JOUR AU - Forbes, J. F. AU - Cuzick, J. AU - Buzdar, A. AU - Howell, A. AU - Tobias, J. S. AU - Baum, M. PY - 2008 DA - 2008// TI - Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 100-month analysis of the ATAC trial JO - Lancet Oncology VL - 9 UR - https://doi.org/10.1016/S1470-2045(07)70385-6 DO - 10.1016/S1470-2045(07)70385-6 ID - Forbes2008 ER - TY - JOUR AU - Muss, H. B. AU - Tu, D. AU - Ingle, J. N. AU - Martino, S. AU - Robert, N. J. AU - Pater, J. L. AU - Whelan, T. J. AU - Palmer, M. J. AU - Piccart, M. J. AU - Shepherd, L. E. AU - Pritchard, K. I. AU - He, Z. AU - Goss, P. E. PY - 2008 DA - 2008// TI - Efficacy, toxicity, and quality of life in older women with early-stage breast cancer treated with letrozole or placebo after 5 years of tamoxifen: NCIC CTG intergroup trial MA.17 JO - J Clin Oncol VL - 26 UR - https://doi.org/10.1200/JCO.2007.12.6334 DO - 10.1200/JCO.2007.12.6334 ID - Muss2008 ER - TY - JOUR AU - Doughty, J. C. PY - 2008 DA - 2008// TI - A review of the BIG results: the Breast International Group 1–98 trial analyses JO - Breast VL - 17 UR - https://doi.org/10.1016/S0960-9776(08)70003-1 DO - 10.1016/S0960-9776(08)70003-1 ID - Doughty2008 ER - TY - JOUR AU - Nilsson, U. W. AU - Garvin, S. AU - Dabrosin, C. PY - 2007 DA - 2007// TI - MMP-2 and MMP-9 activity is regulated by estradiol and tamoxifen in cultured human breast cancer cells JO - Breast Cancer Res Treat VL - 102 UR - https://doi.org/10.1007/s10549-006-9335-4 DO - 10.1007/s10549-006-9335-4 ID - Nilsson2007 ER - TY - JOUR AU - Gee, J. M. AU - Shaw, V. AU - Burmi, R. AU - McClelland, R. AU - Morgan, H. AU - Harper, M. H. S. AU - Barrow, D. AU - Lewis, P. AU - Nicholson, R. I. PY - 2004 DA - 2004// TI - Array profiling of survival and resistance genes in anti-hormone-treated breast cancer cells JO - Intl J Mol Med VL - 14 ID - Gee2004 ER - TY - JOUR AU - Shaw, V. AU - Gee, J. M. W. AU - McClelland, R. A. AU - Morgan, H. AU - Rushmere, N. AU - Nicholson, R. I. PY - 2005 DA - 2005// TI - Identification of anti-hormone induced genes as potential therapeutic targets in breast cancer JO - Proc Amer Assoc Cancer Res VL - 46 ID - Shaw2005 ER - TY - JOUR AU - Platet, N. AU - Cathiard, A. M. AU - Gleizes, M. AU - Garcia, M. PY - 2004 DA - 2004// TI - Estrogens and their receptors in breast cancer progression: a dual role in cancer proliferation and invasion JO - Crit Rev Oncol Hematol VL - 51 UR - https://doi.org/10.1016/j.critrevonc.2004.02.001 DO - 10.1016/j.critrevonc.2004.02.001 ID - Platet2004 ER - TY - JOUR AU - Mathew, A. C. AU - Rajah, T. T. AU - Hurt, G. M. AU - Abbas Abidi, S. M. AU - Dmytryk, J. J. AU - Pento, J. T. PY - 1997 DA - 1997// TI - Influence of antiestrogens on the migration of breast cancer cells using an in vitro wound model JO - Clin Exp Metastasis VL - 15 UR - https://doi.org/10.1023/A:1018498120910 DO - 10.1023/A:1018498120910 ID - Mathew1997 ER - TY - JOUR AU - Rakha, E. A. AU - Abd El Rehim, D. AU - Pinder, S. E. AU - Lewis, S. A. AU - Ellis, I. O. PY - 2005 DA - 2005// TI - E-cadherin expression in invasive non-lobular carcinoma of the breast and its prognostic significance JO - Histopathology VL - 46 UR - https://doi.org/10.1111/j.1365-2559.2005.02156.x DO - 10.1111/j.1365-2559.2005.02156.x ID - Rakha2005 ER - TY - JOUR AU - Gould Rothberg, B. E. AU - Bracken, M. B. PY - 2006 DA - 2006// TI - E-cadherin Immunohistochemical Expression as a Prognostic Factor in Infiltrating Ductal Carcinoma of the Breast: a Systematic Review and Meta-Analysis JO - Breast Cancer Res Treat VL - 100 UR - https://doi.org/10.1007/s10549-006-9248-2 DO - 10.1007/s10549-006-9248-2 ID - Gould Rothberg2006 ER - TY - JOUR AU - Park, D. AU - Karesen, R. AU - Axcrona, U. AU - Noren, T. AU - Sauer, T. PY - 2007 DA - 2007// TI - Expression pattern of adhesion molecules (E-cadherin, alpha-, beta-, gamma-catenin and claudin-7), their influence on survival in primary breast carcinoma, and their corresponding axillary lymph node metastasis JO - APMIS VL - 115 UR - https://doi.org/10.1111/j.1600-0463.2007.apm_524.x DO - 10.1111/j.1600-0463.2007.apm_524.x ID - Park2007 ER - TY - JOUR AU - Summy, J. M. AU - Gallick, G. E. PY - 2003 DA - 2003// TI - Src family kinases in tumor progression and metastasis JO - Cancer Metastasis Rev VL - 22 UR - https://doi.org/10.1023/A:1023772912750 DO - 10.1023/A:1023772912750 ID - Summy2003 ER - TY - JOUR AU - Boyer, B. AU - Roche, S. AU - Denoyelle, M. AU - Thiery, J. P. PY - 1997 DA - 1997// TI - Src and Ras are involved in separate pathways in epithelial cell scattering JO - EMBO journal VL - 16 UR - https://doi.org/10.1093/emboj/16.19.5904 DO - 10.1093/emboj/16.19.5904 ID - Boyer1997 ER - TY - JOUR AU - Avizienyte, E. AU - Frame, M. C. PY - 2005 DA - 2005// TI - Src and FAK signalling controls adhesion fate and the epithelial-to-mesenchymal transition JO - Curr Opin Cell Biol VL - 17 UR - https://doi.org/10.1016/j.ceb.2005.08.007 DO - 10.1016/j.ceb.2005.08.007 ID - Avizienyte2005 ER - TY - JOUR AU - Zheng, A. AU - Kallio, A. AU - Harkonen, P. PY - 2007 DA - 2007// TI - Tamoxifen-induced rapid death of MCF-7 breast cancer cells is mediated via extracellularly signal-regulated kinase signaling and can be abrogated by estrogen JO - Endocrinology VL - 148 UR - https://doi.org/10.1210/en.2006-1269 DO - 10.1210/en.2006-1269 ID - Zheng2007 ER - TY - JOUR AU - Takahashi, K. AU - Suzuki, K. PY - 1996 DA - 1996// TI - Density-dependent inhibition of growth involves prevention of EGF receptor activation by E-cadherin-mediated cell-cell adhesion JO - Exp Cell Res VL - 226 UR - https://doi.org/10.1006/excr.1996.0221 DO - 10.1006/excr.1996.0221 ID - Takahashi1996 ER - TY - JOUR AU - Faux, M. C. AU - Ross, J. L. AU - Meeker, C. AU - Johns, T. AU - Ji, H. AU - Simpson, R. J. AU - Layton, M. J. AU - Burgess, A. W. PY - 2004 DA - 2004// TI - Restoration of full-length adenomatous polyposis coli (APC) protein in a colon cancer cell line enhances cell adhesion JO - J Cell Sci VL - 117 UR - https://doi.org/10.1242/jcs.00862 DO - 10.1242/jcs.00862 ID - Faux2004 ER - TY - JOUR AU - Carothers, A. M. AU - Javid, S. H. AU - Moran, A. E. AU - Hunt, D. H. AU - Redston, M. AU - Bertagnolli, M. M. PY - 2006 DA - 2006// TI - Deficient E-cadherin adhesion in C57BL/6J-Min/+ mice is associated with increased tyrosine kinase activity and RhoA-dependent actomyosin contractility JO - Exp Cell Res VL - 312 UR - https://doi.org/10.1016/j.yexcr.2005.11.019 DO - 10.1016/j.yexcr.2005.11.019 ID - Carothers2006 ER - TY - JOUR AU - Hiscox, S. AU - Jiang, W. G. AU - Obermeier, K. AU - Taylor, K. AU - Morgan, L. AU - Burmi, R. AU - Barrow, D. AU - Nicholson, R. I. PY - 2006 DA - 2006// TI - Tamoxifen resistance in MCF7 cells promotes EMT-like behaviour and involves modulation of beta-catenin phosphorylation JO - Int J Cancer VL - 118 UR - https://doi.org/10.1002/ijc.21355 DO - 10.1002/ijc.21355 ID - Hiscox2006 ER - TY - JOUR AU - Mastracci, T. L. AU - Tjan, S. AU - Bane, A. L. AU - O'Malley, F. P. AU - Andrulis, I. L. PY - 2005 DA - 2005// TI - E-cadherin alterations in atypical lobular hyperplasia and lobular carcinoma in situ of the breast JO - Mod Pathol VL - 18 UR - https://doi.org/10.1038/modpathol.3800362 DO - 10.1038/modpathol.3800362 ID - Mastracci2005 ER - TY - JOUR AU - Rakha, E. A. AU - El-Sayed, M. E. AU - Powe, D. G. AU - Green, A. R. AU - Habashy, H. AU - Grainge, M. J. AU - Robertson, J. F. AU - Blamey, R. AU - Gee, J. AU - Nicholson, R. I. AU - Lee, A. H. AU - Ellis, I. O. PY - 2008 DA - 2008// TI - Invasive lobular carcinoma of the breast: response to hormonal therapy and outcomes JO - Eur J Cancer VL - 44 UR - https://doi.org/10.1016/j.ejca.2007.10.009 DO - 10.1016/j.ejca.2007.10.009 ID - Rakha2008 ER - TY - JOUR AU - Korkola, J. E. AU - DeVries, S. AU - Fridlyand, J. AU - Hwang, E. S. AU - Estep, A. L. AU - Chen, Y. Y. AU - Chew, K. L. AU - Dairkee, S. H. AU - Jensen, R. M. AU - Waldman, F. M. PY - 2003 DA - 2003// TI - Differentiation of lobular versus ductal breast carcinomas by expression microarray analysis JO - Cancer Res VL - 63 ID - Korkola2003 ER - TY - JOUR AU - Cleton-Jansen, A. M. PY - 2002 DA - 2002// TI - E-cadherin and loss of heterozygosity at chromosome 16 in breast carcinogenesis: different genetic pathways in ductal and lobular breast cancer? JO - Breast Cancer Res VL - 4 UR - https://doi.org/10.1186/bcr416 DO - 10.1186/bcr416 ID - Cleton-Jansen2002 ER - TY - JOUR AU - Pestalozzi, B. C. AU - Zahrieh, D. AU - Mallon, E. AU - Gusterson, B. A. AU - Price, K. N. AU - Gelber, R. D. AU - Holmberg, S. B. AU - Lindtner, J. AU - Snyder, R. AU - Thurlimann, B. AU - Murray, E. AU - Viale, G. AU - Castiglione-Gertsch, M. AU - Coates, A. S. AU - Goldhirsch, A. PY - 2008 DA - 2008// TI - Distinct clinical and prognostic features of infiltrating lobular carcinoma of the breast: combined results of 15 International Breast Cancer Study Group clinical trials JO - J Clin Oncol VL - 26 UR - https://doi.org/10.1200/JCO.2007.14.9336 DO - 10.1200/JCO.2007.14.9336 ID - Pestalozzi2008 ER - TY - JOUR PY - 2007 DA - 2007// TI - Ovarian ablation or suppression in premenopausal early breast cancer: results from the international adjuvant breast cancer ovarian ablation or suppression randomized trial JO - J Natl Cancer Inst VL - 99 UR - https://doi.org/10.1093/jnci/djk109 DO - 10.1093/jnci/djk109 ID - ref49 ER -