Figure 5
From: PAI-1 and functional blockade of SNAI1 in breast cancer cell migration
Modified distribution of Plasminogen Activator Inhibitor type-1 (PAI-1) in SNAI1-DN cells. PAI-1 immunostaining is rarely co-localied with F-actin structures in MDA-mock cells. In these cells, PAI-1 is preferentially localised in the perinuclear region. In contrast in SNAI1-DN-cells, PAI-1 immunostaining is strongly localised in the numerous lamellipodia and is more diffuse in the cytoplasm.