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Figure 3 | Breast Cancer Research

Figure 3

From: PAI-1 and functional blockade of SNAI1 in breast cancer cell migration

Figure 3

Quantitative changes in SNAI1-DN cell migration. The migratory behaviour of MDA-mock and SNAI1-DN cells is analysed in an in vitro wound healing assay. Monolayer cell cultures of MDA-mock and SNAI1-DN cells are gently scratched with a pipette tip to produce a wound. (a) Photographs of the cultures are taken immediately after the incision, and after three and five hours in culture. (b) The extent of wound closure is determined after three and five hours incubation. The comparison of MDA-mock and SNAI1-DN migration shows that SNAI1-DN cells migrate significantly more slowly than MDA-mock cells five hours after wounding. Mean values (standard error of the mean) of four independent assays are shown.* p < 0.05.

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