Linkage disequilibrium plots for polymorphisms in the DCN and LUM genes. Linkage disequilibrium (LD) plots for polymorphisms in the Mayo Clinic sample, 2001 to 2005, for (a) the decorin (DCN) gene and (b) the lumican (LUM) gene. Shaded regions indicate strength of LD between pairwise combinations of polymorphisms (white, r2 = low LD; black, r2 = near-perfect LD). Numbers in squares indicate estimates of the pairwise r2. DCN SNP rs3138268 had minor allele frequency = 0 (absent in figure), and DCN SNPs rs3138165, rs2070985 and rs13312816 had pairwise r2 ≥ 0.98: only rs3138165 was included in the statistical analyses.