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Figure 3 | Breast Cancer Research

Figure 3

From: Serial analysis of gene expression of lobular carcinoma in situ identifies down regulation of claudin 4 and overexpression of matrix metalloproteinase 9

Figure 3

Claudin 4 immunohistochemistry (IHC) in separate lobular carcinoma in situ (LCIS) cases. (a) H & E section of LCIS case 1. (b) Claudin 4 IHC of LCIS case 1. Note the intact labelling of undermined residual strips of luminal epithelium and diminished expression in LCIS cells. (c) H & E section of LCIS case 2. (d) Claudin 4 IHC of LCIS case 2. Note the intact labelling of residual luminal epithelium and diminished expression in LCIS cells which undermine the luminal epithelium.

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Breast Cancer Research

ISSN: 1465-542X

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