Figure 1
From: Selective segregation of DNA strands persists in long label retaining mammary cells during pregnancy
LRC are in cycle during pregnancy. The nuclear label [3H]-thymidine is detected by autoradiography in sections of mammary tissue from pregnant mice that received 5BrdU for 2 weeks during weeks 4 and 5 of life (group 1 is day 3 of pregnancy, group 2 is day 4 of pregnancy, group 3 is day 6 of pregnancy, and group 4 is day 12 of pregnancy). LRC in periductal and basal positions are evident in all time points evaluated. Arrows indicate double positive cells. Scale bars = 10 μm. 5BrdU, 5-bromodeoxyuridine; LRC, label-retaining cell.