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Table 3 Cox univariate regression of recurrence-free survival in the treated arm of Cohort II

From: Novel image analysis approach for quantifying expression of nuclear proteins assessed by immunohistochemistry: application to measurement of oestrogen and progesterone receptor levels in breast cancer

 

Cohort II treated arm (n = 276)

 

Oestrogen receptor

Progesterone receptor

 

HR

95% CI

P value

HR

95% CI

P value

Manual analysis

0.622

0.413 to 0.936

0.023

0.566

0.368 to 0.869

0.009

Automated 10% threshold

0.666

0.434 to 1.022

0.063

0.64

0.534 to 0.955

0.04

Automated clustering

0.579

0.384 to 0.872

0.009

0.67

0.431 to 1.043

0.07

  1. HR, hazard ratio; CI, confidence interval.
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Breast Cancer Research

ISSN: 1465-542X

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