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Table 3 Cox univariate regression of recurrence-free survival in the treated arm of Cohort II

From: Novel image analysis approach for quantifying expression of nuclear proteins assessed by immunohistochemistry: application to measurement of oestrogen and progesterone receptor levels in breast cancer

  Cohort II treated arm (n = 276)
  Oestrogen receptor Progesterone receptor
  HR 95% CI P value HR 95% CI P value
Manual analysis 0.622 0.413 to 0.936 0.023 0.566 0.368 to 0.869 0.009
Automated 10% threshold 0.666 0.434 to 1.022 0.063 0.64 0.534 to 0.955 0.04
Automated clustering 0.579 0.384 to 0.872 0.009 0.67 0.431 to 1.043 0.07
  1. HR, hazard ratio; CI, confidence interval.