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Table 5 Genes selected for quantitative RT-PCR experiments using an independent sample set of in situ component of DCIS/IDC (11 samples)

From: Evidence that molecular changes in cells occur before morphological alterations during the progression of breast ductal carcinoma

 

Gene symbol

Microarray (fold change)

Quantitative RT-PCR (fold change)

Target genes

C16orf5

5.5

1.4

 

GOSR2

4.0

6.4a

 

LOX

-2.0

-3.6a

 

SULF-1

-4.0

-37a

 

TXNL2

4.2

-13.4

  1. Positive and negative numbers indicate upregulated and downregulated genes in pure DCIS, respectively. aGenes confirmed using both methodologies. DCIS, ductal carcinoma in situ; IDC, invasive ductal carcinoma.