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Figure 3 | Breast Cancer Research

Figure 3

From: Wnt signalling in human breast cancer: expression of the putative Wnt inhibitor Dickkopf-3 (DKK3) is frequently suppressed by promoter hypermethylation in mammary tumours

Figure 3

DKK3 mRNA expression analysis in primary breast carcinomas. (a) Realtime PCR of DKK3 mRNA expression in 19 matched pairs (normal vs. tumour). Arrowheads indicate downregulation in the tumour by an expression fold change of more than two (FC2). (b) Relative DKK3 mRNA expression in 40 additional breast cancer specimens. Mean expression of 19 normal breast tissues (N) was set to 1. Based on a FC2, grey bars represent tumour specimens (T) showing normal expression, black bars represent tumour specimens with reduced DKK3 mRNA expression.

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Breast Cancer Research

ISSN: 1465-542X

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