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Table 2 Patient characteristics: metastatic disease

From: Phosphorylated EGFR and PI3K/Akt signaling kinases are expressed in circulating tumor cells of breast cancer patients

Characteristic

n (%)

Menopausal status

   Premenopausal

5 (31)

   Postmenopausal

9 (56)

   Unknown

2 (13)

Disease sites

   1

1 (6)

   2

7 (44)

   3

6 (38)

   ≥ 4

2 (12)

Predominantly visceral disease

   Yes

3 (19)

   No

13 (81)

Line of treatment

   0

3 (19)

   1

6 (37)

   2

3 (19)

   ≥- 3

4 (25)

ER/PR tumor status

   Positive

11 (69)

   Negative

5 (31)

HER2 tumor status

   Positivea

5 (31)

   Negative

11(69)

EGFR tumor status

   Positive

1(6)

   Negative

9 (56)

   Unknown

6 (38)

  1. aA score +3 or fluorescence in situ hybridization positive. EGFR, epidermal growth factor receptor; ER, estrogen receptor; HER, human epidermal growth factor receptor; PR, progesterone receptor.