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Table 2 Patient characteristics: metastatic disease

From: Phosphorylated EGFR and PI3K/Akt signaling kinases are expressed in circulating tumor cells of breast cancer patients

Characteristic n (%)
Menopausal status
   Premenopausal 5 (31)
   Postmenopausal 9 (56)
   Unknown 2 (13)
Disease sites
   1 1 (6)
   2 7 (44)
   3 6 (38)
   ≥ 4 2 (12)
Predominantly visceral disease
   Yes 3 (19)
   No 13 (81)
Line of treatment
   0 3 (19)
   1 6 (37)
   2 3 (19)
   ≥- 3 4 (25)
ER/PR tumor status
   Positive 11 (69)
   Negative 5 (31)
HER2 tumor status
   Positivea 5 (31)
   Negative 11(69)
EGFR tumor status
   Positive 1(6)
   Negative 9 (56)
   Unknown 6 (38)
  1. aA score +3 or fluorescence in situ hybridization positive. EGFR, epidermal growth factor receptor; ER, estrogen receptor; HER, human epidermal growth factor receptor; PR, progesterone receptor.
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