TY - JOUR AU - Loibl, Sibylle AU - von Minckwitz, Gunter AU - Harbeck, Nadia AU - Janni, Wolfgang AU - Elling, Dirk AU - Kaufmann, Manfred AU - Eggemann, Holm AU - Nekljudova, Valentina AU - Sommer, Harald AU - Kiechle, Marion AU - Kümmel, Sherko PY - 2008 DA - 2008/09/16 TI - Clinical feasibility of (neo)adjuvant taxane-based chemotherapy in older patients: analysis of >4,500 patients from four German randomized breast cancer trials JO - Breast Cancer Research SP - R77 VL - 10 IS - 5 AB - Despite the fact that people older than 65 years of age have the highest incidence of developing breast cancer, these patients are excluded from clinical trials in most cases. Furthermore, most physicians tend towards therapy regimens without the use of dose-dense, highly active taxane-based treatments because of a lack of data regarding toxicities of these compounds in older patients. SN - 1465-542X UR - https://doi.org/10.1186/bcr2144 DO - 10.1186/bcr2144 ID - Loibl2008 ER -