Table 4 Comparison of ERα status of the primary tumour and metastatic lesion§
From: ERalpha-status of disseminated tumour cells in bone marrow of primary breast cancer patients
Author | N | Primary tumour ER + % | ER discordance rate (%) | Site of metastasis | Change ER+/ER- N (%) | Change ER-/ER+ N (%) |
|---|---|---|---|---|---|---|
Nomura et al. [35] | 42 | 64 | 10 (24) | LR | 10 (24) | 0 |
Kuukasjarvi et al. [25] | 50 | 70 | 12 (24) | LR, MET | 12 (24) | 0 |
Lower et al. [36] | 200 | 58 | 60 (30) | MET | 39 (20) | 21 (11) |
Li et al. [37] | 83 | 76 | 24 (29) | LR, MET | 83 (16) | 11 (13) |
Fernandez et al. [27] | 26 | 65 | (35) | LN | 6 (23) | 0 |
Raemaekers et al. [38] | 75 | 58 | 14 (19) | LR, LN | 8 (10) | 6 (8) |
Zheng et al. [26] | 52 | 54 | (10) | LN | 3 (10) | 0 |
Ditsch et al. [16] | 17 | 64 | 9 (53) | DTC | 9 (53) | 0 |
Broom et al. [28] | 62 | 18 | 11 (18) | DTC, LN, MET | 6 (10) | 5 (8) |
Our study | 107 | 82 | 77 (82) | BM | 76 (71) | 1 (1) |