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Table 2 Comparison of p16INK4a immunohistochemistry and RB1 LOH status

From: The functional loss of the retinoblastoma tumour suppressor is a common event in basal-like and luminal B breast carcinomas

 

p16 IHC 0

1+

2+

3+

Total

 

RB1 LOH

      

LOH-

9 (23.7)

11 (29.0)

11 (29.0)

7 (18.4)

38

 

LOH+

1 (3.9)

8 (30.8)

5 (19.2)

12 (46.2)

26

 
 

10

19

16

19

64

p = 0.0369

  1. 0 = negative, 1+ = weak positive, 2+ = moderate positive, 3+ = strong positive. P-values determined by Chi-square test.
  2. IHC = immunohistochemistry; LOH = loss of heterozygosity; RB1 = retinoblastoma.
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Breast Cancer Research

ISSN: 1465-542X

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