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Table 3 Age and age-standardised characteristics of breast cancer cases, Nurses' Health Study (1976 to 1996)

From: Comparison of molecular phenotypes of ductal carcinoma in situand invasive breast cancer

Risk factors DCIS (n = 272) Invasive (n = 2249)
Means   
Age at diagnosis, y 57.9 57.3
Age at menopause, y 45.2 45.5
Age at menarche, y 12.3 12.4
Body mass index at age 18, kg/m2 20.9 21.0
Paritya 3.1 3.2
Age at first birtha, y 24.9 25.4
Alcohol, g/week 5.7 6.3
Frequency, %   
Family history of breast cancer 19.0 13.3
Nulliparous 6.9 6.9
Premenopausal at diagnosis 22.4 20.8
Postmenopausal at diagnosis 76.2 77.2
Prior benign breast disease 57.0 44.8
Current postmenopausal hormone useb 37.3 31.9
Molecular Markers, %   
ER positive 74.0 77.0
PR positive 59.9 64.4
HER2 positive 27.2 10.9
  1. aAmong parous women only. bAmong postmenopausal women only. DCIS, ductal carcinoma in situ; ER, oestrogen receptor; HER2, human epidermal growth factor receptor 2; PR, progesterone receptor.