Meta-analysis of gene expression profiles in breast cancer: toward a unified understanding of breast cancer subtyping and prognosis signatures

Table 2 Prognostic signatures

Signature symbol	Reference	Associated variables in gene selection procedure	Number of genes
			Original probes	Mapped to geneID
ONC-16	[42]	Biological knowledge; refined by patient outcome	16	16
NKI-70	[19]	Patient outcome	70	52
EMC-76	[21]	Patient outcome, stratified by estrogen receptor status	60 + 16	48 + 12
NCH-70	[12]	Patient outcome	70	69
CON-52	[43]	Patient outcome, consensus	52	50
p53-32	[11]	p53 mutation	32	19
CSR	[24]	Fibroblast core serum response	512	457
GGI-128	[18]	Histological grade	128	98
CCYC	[44]	Periodic expression in cell cycle progression	NA	126

ISSN: 1465-542X