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Figure 1 | Breast Cancer Research

Figure 1

From: Over-expression of Skp2 is associated with resistance to preoperative doxorubicin-based chemotherapy in primary breast cancer

Figure 1

Representative immunohistochemistry slides for Skp2 and p27Kip1 staining in locally advanced breast cancer. Tumor cells of pretreated grade II invasive duct cancer (T3N1MO) exhibiting strong and diffuse nuclear staining for Skp2 and low staining of p27Kip1 (upper row and insert). Note the inversely low Skp2 staining followed by high p27Kip1 staining in normal breast tissue (lower row). KIP, kinase inhibitor protein; Skp2, S-phase kinase protein 2.

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