Table 3 Gene lists identified from the canonical pathway analyses shown in Figure 3b

ERK/MAPK signaling

ARAF, CREB3, CREB5, DUSP4, EGFR, ELF3, FGFR3, FGFR4, FYN, HSPB2, LTK, MERTK, MKNK1, MYCN, PIK3R2, PIK3R3, PIK3R5, PLCG2, PPM1J, PPP1CB, PPP1R10, PPP1R11, PPP1R14A, PPP2R1B, PRKACG, PRKAG2, PRKAR1A, PRKCG, RAC1, RAC2, RAPGEF1, RAPGEF4, ROR2, RPS6KA5, SHC1

ATF4, ELK1, ESR1, FOS, MAPKAPK5, MRAS, MYC, PIK3CA, PLA2G2A, PLA2G6, PPP1R3D, PPP1R7, PRKACA, PRKCD, STAT1

Axonal guidance signaling

ADAM2, ADAM30, ARHGEF12, BAIAP2, BDNF, BMP6, BMP8A, BMP8B, CFL2, DPYSL5, EFNB3, EGFR, EPHA10, EPHA8, EPHB1, FGFR3, FGFR4, FYN, GLI1, GLI2, GNAL, GNAO1, GNAT2, GNG3, L1CAM, LTK, MAG, MERTK, MICAL1, MKNK1, MYL5, MYL7, NFATC1, NFATC4, NGFB, NTF5, PIK3R2, PIK

ABLIM1, ADAM9, BMP15, CDC42, EPHA3, EPHB4, GNAS, KALRN, MRAS, MYL3, NFATC2, NTF3, NTN2L, PIK3CA, PRKACA, PRKCD, ROBO1, SMO, SRGAP3, WASL, WNT16, WNT2

B-cell receptor signaling

BCL10, BCL2A1, BCL3, CALM3, CAMK2B, CARD10, CREB3, CREB5, GSK3A, INPP5D, LYN, MAP2K4, MAP3K11, MAPK13, NFATC1, NFATC4, NFKBIE, PIK3R2, PIK3R3, PIK3R5, PLCG2, POU2F2, PRKCQ, PTEN, RAC1, RAC2, RELA, SHC1

ATF4, BCL6, CDC42, CHUK, ELK1, FCGR2A, FCGR2B, FCGR2C, MAP2K7, MRAS, NFATC2, PIK3CA

Integrin signaling

ACTA1, ACTB, ACTG2, ACTN3, ACTN4, BCAR3, CAPN5, CAPN9, CAPNS1, EGFR, FGFR3, FGFR4, FYN, ITGAX, LTK, MAP2K4, MAP3K11, MERTK, MRCL3, MRLC2, MYL5, MYL7, PIK3R2, PIK3R3, PIK3R5, PLCG2, PPP1CB, PTEN, RAC1, RAC2, RALA, RAPGEF1, RHOC, RHOT2, ROR2, SHC1, TLN1, TN

ARF5, CAV1, CDC42, DDEF1, ITGA10, ITGB2, MRAS, MYLK, PIK3CA, TSPAN3, WASL

Huntington's disease signaling

BDNF, BET1L, CACNA1B, CAPN5, CAPN9, CAPNS1, CREB3, CREB5, DNM3, EGFR, GNG3, HAP1, HSPA1A, HSPA1B, HSPA2, HSPA8, IGF1R, MAP2K4, MAPK13, NAPA, NAPG, NCOR2, NGFB, PACSIN1, PIK3R2, PIK3R3, PIK3R5, POLR2C, POLR2D, POLR2H, POLR2J, PRKCG, PRKCH, PRKCQ, SHC1, SNA

ATF4, CASP2, CASP4, DLG4, DNAJC5, EP300, HDAC7A, MAP2K7, MAPK6, PIK3CA, PRKCD, SDHA, SDHB, STX16, VAMP3, YKT6