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Table 2 Top 20 putative hypomethylated gene targets detected by promoter analyses of 468GFP and 468LN cells

From: Epigenetic mapping and functional analysis in a breast cancer metastasis model using whole-genome promoter tiling microarrays

Description Gene symbol Chromosome Fold change
Chromogranin A (parathyroid secretory protein 1) CHGA 14q32 6.44
DKFZP434B0335 protein DKFZP434B0335 7q21.3 3.73
Zinc finger, C3HC-type containing 1 ZC3HC1 7q32.2 3.41
Centrosomal protein 57 kDa CEP57 11q21 3.22
Stromal antigen 1 STAG1 3q22.3 3.12
Vesicle-associated membrane protein 3 (cellubrevin) VAMP3 1q36.23 3.07
Ectonucleoside triphosphate diphosphohydrolase 7 ENTPD7 10q24.2 2.98
Transmembrane emp24 domain trafficking protein 2 TMED2 12q24.31 2.97
Glycoprotein V (platelet) GP5 3q29 2.96
CATR tumorigenicity conversion 1 CATR1 7q32 2.87
Nuclear receptor subfamily 2, group C, member 2 NR2C2 3p25 2.83
Small EDRK-rich factor 1A (telomeric) SERF1A 5q12.2-q13.3 2.83
Transcription factor 12 TCF12 15q21 2.82
Zinc finger and BTB domain containing 20 ZBTB20 3q13.2 2.82
Aurora kinase A interacting protein 1 AURKAIP1 1p36.33 2.82
Sorting nexin 1 SNX1 15q22.31 2.82
LOC136263 LOC136263 7q32.2 2.81
NEDD8 ultimate buster-1 NYREN18 7q36 2.77
Testis specific, 13 TSGA13 7q32 2.76
Solute carrier family 3A, member 2 SLC3A2 11q13 2.75
  1. The names and descriptions of the genes are given, as well as the fold change in hypomethylation in MDA-MB-468GFP-LN (468LN) cells relative to MDA-MB-468GFP (468GFP) cells.