Table 1 Top 20 putative hypermethylated gene targets detected by promoter analyses of 468GFP and 468LN cells
Gene name | Common name | Chromosome | Fold change |
|---|---|---|---|
FK506 binding protein 9, 63 kDa | FKBP9 | 7p11.1 | 6.02 |
EGFR-coamplified and overexpressed protein | ECOP | 7p11.2 | 5.89 |
Hypothetical protein MGC33530 | MGC33530 | 7p11.2 | 5.07 |
LanC lantibiotic synthetase component C-like 2 | LANCL2 | 7p11.2 | 4.72 |
Coiled-coil-helix–coiled-coil–helix domain containing 2 | CHCHD2 | 7p11.2 | 4.55 |
Epidermal growth factor receptor | EGFR | 7p11.2 | 4.54 |
FK506 binding protein 9, 63 kDa | FKBP9 | 7p11.2 | 3.99 |
Immunoglobulin heavy locus | IGH@ | 14q32.33 | 3.89 |
ATPase, H+, lysosomal 42 kDa, V1 subunit C1 | ATP6V1C1 | 8q22.3 | 3.86 |
Beta 1,3-galactosaminyltransferase, polypeptide 1 | B3GALNT1 | 3q25 | 3.45 |
Sec61 gamma subunit | SEC61G | 7p11.2 | 3.45 |
Kelch-like 26 (Drosophila) | KLHL26 | 19p13.11 | 3.44 |
phospholipase C, gamma 2 | PLCG2 | 16q24.1 | 3.41 |
Ubiquitin specific peptidase 49 | USP49 | 6p21 | 3.20 |
Solute carrier family 22, member 6 | SLC22A6 | 11q13.1 | 3.07 |
Similar to metallo-beta-lactamase superfamily protein | LOC153364 | 5q14.3 | 3.05 |
Src homology 2 domain containing adaptor protein B | SHB | 9p12 | 3.05 |
Cholinergic receptor, nicotinic, delta | CHRND | 2q33 | 2.92 |
Down syndrome critical region gene 9 | DSCR9 | 21q21.13 | 2.83 |
Membrane associated ring protein 8 | C3HC4 | 10q11.21 | 2.75 |