Table 7 Likelihood of having a BRCA1 or BRCA2 deleterious mutations
Personal history | Family history | Total | BRCA1positive | BRCA2positive | BRCApositive | BRCApositive |
|---|---|---|---|---|---|---|
| Â | Â | Â | Number | Number | Number | % |
Breast cancer <50 years | Nil | 61 | 2 | 3 | 5 | 8.2 |
Breast cancer <50 years | 1 breast cancer <50 years | 29 | 1 | 3 | 4 | 13.8 |
Breast cancer ≥ 50 years | 1 breast cancer <50 years | 13 | 1 | 0 | 1 | 7.7 |
Breast cancer at any age | ≥ 2 breast cancer <50 years | 7 | 1 | 0 | 1 | 14.3 |
Breast cancer at any age | ≥ 3 breast cancer at any age | 9 | 0 | 3 | 3 | 33.3 |
Breast cancer at any age | ≥ 1 ovarian cancer at any age | 10 | 4 | 1 | 5 | 50.0 |
Breast and ovarian cancer | Any | 5 | 2 | 1 | 3 | 60.0 |
Bilateral breast cancer | Any | 25 | 4 | 1 | 5 | 20.0 |