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Table 7 Likelihood of having a BRCA1 or BRCA2 deleterious mutations

From: Evaluation of BRCA1 and BRCA2 mutations and risk-prediction models in a typical Asian country (Malaysia) with a relatively low incidence of breast cancer

Personal history Family history Total BRCA1positive BRCA2positive BRCApositive BRCApositive
    Number Number Number %
Breast cancer <50 years Nil 61 2 3 5 8.2
Breast cancer <50 years 1 breast cancer <50 years 29 1 3 4 13.8
Breast cancer ≥ 50 years 1 breast cancer <50 years 13 1 0 1 7.7
Breast cancer at any age ≥ 2 breast cancer <50 years 7 1 0 1 14.3
Breast cancer at any age ≥ 3 breast cancer at any age 9 0 3 3 33.3
Breast cancer at any age ≥ 1 ovarian cancer at any age 10 4 1 5 50.0
Breast and ovarian cancer Any 5 2 1 3 60.0
Bilateral breast cancer Any 25 4 1 5 20.0