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Table 2 Imputation of log estradiol using data from the Nurses' Health Study breast cancer nested case-control studya

From: Risk prediction models with incomplete data with application to prediction of estrogen receptor-positive breast cancer: prospective data from the Nurses' Health Study

Variable Beta Standard error P value
Intercept 2.241 0.085  
Case status 0.130 0.048 0.008
Body mass index (postmenopausal)b 0.0033 0.0003 <0.001
Birth indexc -0.0021 0.0006 <0.001
Duration of natural menopause -0.015 0.004 <0.001
Duration of menopause after bilateral oophorectomy -0.013 0.004 0.004
R 2 = 0.219    
  1. aBased on 164 cases and 346 controls. bDuration postmenopause × average body mass index postmenopause. cBirth index = i = 1 s t ( t m t i ) b i t MathType@MTEF@5@5@+=feaagaart1ev2aaatCvAUfKttLearuqqRPxAKvMB6bYrY9gDLn3AGiuraeXatLxBI9gBaebbnrfifHhDYfgasaacPi6xNi=xH8viVGI8Gi=hEeeu0xXdbba9frFj0xb9qqpG0dXdb9aspeI8k8fiI+fsY=rqGqVepae9pg0db9vqaiVgFr0xfr=xfr=xc9adbaqaaeGaciGaaiaabeqaaeqabiWaaaGcbaWaaabCaeaacqGGOaakcqWG0baDdaWgaaWcbaGaemyBa0gabeaakiabgkHiTiabdsha0naaBaaaleaacqWGPbqAaeqaaaqaaiabdMgaPjabg2da9iabigdaXaqaaiabdohaZXGaemiDaqhaniabggHiLdGccqGGPaqkcqWGIbGydaWgaaWcbaGaemyAaKMaemiDaqhabeaaaaa@4334@ if parous and = 0 if nulliparous where s = parity; t i = age at ith birth, i = 1, ..., s; t m = age at menopause; and b it = 1 if parity is greater than or equal to i at age t and = 0 otherwise.