Figure 1
From: PMC42, a breast progenitor cancer cell line, has normal-like mRNA and microRNA transcriptomes
Analysis of mRNA gene expression in breast cell lines and normal tissue. (a) Analysis of differentially expressed mRNAs. Clustering heatmap for genes with analysis of variance B values of greater than 10 after either a median or a quantile normalisation. Cell type origin (B, basal; L, luminal; N, normal; S?, possible stem cell) and status of oestrogen receptor/progesterone receptor (ER/PR) are indicated on the left. mRNA clusters are indicated by purple letters (below, with their key enriched process) and purple arrows (above and below). ECM, extracellular matrix; VR, viral response. (b) Analysis of luminal/basal mRNA markers. The average log2 intensity of expression of 252 luminal and 360 basal annotated non-redundant markers is shown.