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Figure 1 | Breast Cancer Research

Figure 1

From: PMC42, a breast progenitor cancer cell line, has normal-like mRNA and microRNA transcriptomes

Figure 1

Analysis of mRNA gene expression in breast cell lines and normal tissue. (a) Analysis of differentially expressed mRNAs. Clustering heatmap for genes with analysis of variance B values of greater than 10 after either a median or a quantile normalisation. Cell type origin (B, basal; L, luminal; N, normal; S?, possible stem cell) and status of oestrogen receptor/progesterone receptor (ER/PR) are indicated on the left. mRNA clusters are indicated by purple letters (below, with their key enriched process) and purple arrows (above and below). ECM, extracellular matrix; VR, viral response. (b) Analysis of luminal/basal mRNA markers. The average log2 intensity of expression of 252 luminal and 360 basal annotated non-redundant markers is shown.

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