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Table 5 Top 20 genes differing between tumor with and without the presence of CD44+/CD24- tumor cells

From: The CD44+/CD24-phenotype is enriched in basal-like breast tumors

Rank

Clonea

Gene descriptionb

Gene symbol

Signc

1

1499830

Myocardial infarction associated transcript (nonprotein coding)

MIAT

-

2

82421

CD44 molecule (Indian blood group)

CD44

+

3

2018758

Peroxisomal biogenesis factor 7

PEX7

+

4

320712

Protein kinase, X-linked, pseudogene 1

PRKXP1

-

5

824908

Transmembrane protein 49

TMEM49

-

6

328868

CD44 molecule (Indian blood group)

CD44

+

7

1472689

Apolipoprotein C-I

APOC1

-

8

126341

Myosin, light chain kinase

MYLK

+

9

1609752

Apolipoprotein C-I

APOC1

-

10

811028

Transmembrane protein 49

TMEM49

-

11

788714

Ataxin 10

ATXN10

+

12

310019

Myosin, light chain kinase

MYLK

+

13

137296

SEC24 related gene family, member A (S. cerevisiae)

SEC24A

-

14

32493

Integrin, α6

ITGA6

+

15

754582

Ecotropic viral integration site 2A

EVI2A

-

16

1159963

Interferon regulatory factor 7

IRF7

-

17

612576

3-Oxoacid CoA transferase 1

OXCT1

+

18

503724

Transcribed locus, strongly similar to NP_034722.1 jun D proto-oncogene (Mus musculus)

Unavailable data

+

19

810463

Dehydrogenase/reductase (SDR family) member 7B

DHRS7B

-

20

502067

Lupus brain antigen 1

LBA1

-

  1. aIntegrated Molecular Analysis of Genomes and their Expression (IMAGE) consortium cDNA clone number. bClones mapped using UniGene Build 208 (National Center for Biotechnology Information, Bethesda, Maryland, USA). cGenes are either upregulated (+) or downregulated (-) in tumors containing CD44+/CD24- tumor cells.