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Table 3 Association of CD44/CD24 phenotypes with breast cancer subgroups.

From: The CD44+/CD24-phenotype is enriched in basal-like breast tumors

Phenotype All tumors (n = 232) SR+HER2- (n = 150) SR+HER2+ (n = 14) SR-HER2+ (n = 24) SR-HER2- P valuea
      Basal-like (n = 30) Nonbasal (n = 14)  
CD44        0.001
   Positive (> 0%) 75 (32) 47 (31) 2 (14) 4 (17) 19 (63) 3 (21)  
   Negative 157 (68) 103 (69) 12 (86) 20 (83) 11 (37) 11 (78)  
CD24        0.035
   Positive (> 0%) 108 (47) 65 (43) 8 (57) 18 (75) 12 (40) 5 (36)  
   Negative 124 (53) 85 (57) 6 (43) 6 (25) 18 (60) 9 (64)  
CD44+/CD24-        < 0.001
   Positive (> 0%) 73 (31) 47 (31) 2 (14) 2 (8) 19 (63) 3 (21)  
   Negative 159 (69) 103 (69) 12 (86) 22 (92) 11 (37) 11 (79)  
CD44-/CD24+        0.027
   Positive (> 0%) 106 (46) 63 (42) 8 (57) 18 (75) 12 (40) 5 (36)  
   Negative 126 (54) 87 (58) 6 (43) 6 (25) 18 (60) 9 (64)  
CD44+/CD24+        0.61
   Positive (> 0%) 14 (6) 9 (6) 0 (0) 3 (12) 2 (7) 0 (0)  
   Negative 218 (94) 141 (94) 14 (100) 21 (88) 28 (93) 14 (100)  
CD44-/CD24-        0.28
   100% 78 (28) 57 (31) 4 (24) 5 (18) 6 (18) 6 (40)  
   < 100% 197 (72) 125 (69) 13 (76) 23 (82) 27 (82) 9 (60)  
  1. Data presented as n (%). SR, steroid receptor. aP values were calculated using Fisher's exact test.